The human early-life exposome (HELIX): project rationale and design
…, D van Gent, JR Gonzalez, B Granum… - Environmental …, 2014 - ehp.niehs.nih.gov
Background: Developmental periods in early life may be particularly vulnerable to impacts
of environmental exposures. Human research on this topic has generally focused on single …
of environmental exposures. Human research on this topic has generally focused on single …
[HTML][HTML] Consideration of pathways for immunotoxicity of per-and polyfluoroalkyl substances (PFAS)
…, R Vandebriel, B Granum, M Luijten, B Lindeman… - Environmental …, 2023 - Springer
… by regulatory agencies for the evaluation of the immunotoxic potential of pharmaceuticals
and chemicals, as they are a robust and sensitive method and provide a functional readout of B…
and chemicals, as they are a robust and sensitive method and provide a functional readout of B…
Pre-natal exposure to perfluoroalkyl substances may be associated with altered vaccine antibody levels and immune-related health outcomes in early childhood
B Granum, LS Haug, E Namork… - Journal of …, 2013 - Taylor & Francis
Perfluoroalkyl substances (PFAS) are suggested to have immunosuppressive effects; exposure
in utero and in the first years of life is of special concern as fetuses and small children …
in utero and in the first years of life is of special concern as fetuses and small children …
The effect of particles on allergic immune responses
B Granum, M Løvik - Toxicological Sciences, 2002 - academic.oup.com
… alone; Granum et al., 2001a). Similar effects were found after intranasal or intratracheal
instillation with OVA plus PSP or silica particles to naıve NIH/Ola mice (Granum et al., 2001a, b). …
instillation with OVA plus PSP or silica particles to naıve NIH/Ola mice (Granum et al., 2001a, b). …
Early food intervention and skin emollients to prevent food allergy in young children (PreventADALL): a factorial, multicentre, cluster-randomised trial
…, ÅW Despriee, M Färdig, SW Gerdin, B Granum… - The Lancet, 2022 - thelancet.com
Background Primary prevention of food allergy by early introduction of allergenic foods
seems promising. We aimed to determine whether early food introduction or the application of …
seems promising. We aimed to determine whether early food introduction or the application of …
Asthma in every fifth child in Oslo, Norway: a 10‐year follow up of a birth cohort study
…, M Munthe‐Kaas, M Pettersen, B Granum… - Allergy, 2006 - Wiley Online Library
Background: The western world's increase in childhood asthma is suggested to level off. We
aimed to investigate asthma prevalence in 10‐year‐old children within the prospective birth …
aimed to investigate asthma prevalence in 10‐year‐old children within the prospective birth …
Skin emollient and early complementary feeding to prevent infant atopic dermatitis (PreventADALL): a factorial, multicentre, cluster-randomised trial
…, EM Rehbinder, R Vettukattil, M LeBlanc, B Granum… - The Lancet, 2020 - thelancet.com
Background Skin emollients applied during early infancy could prevent atopic dermatitis, and
early complementary food introduction might reduce food allergy in high-risk infants. The …
early complementary food introduction might reduce food allergy in high-risk infants. The …
Human Early Life Exposome (HELIX) study: a European population-based exposome cohort
…, L Giorgis-Allemand, JR Gonzalez, B Granum… - BMJ open, 2018 - bmjopen.bmj.com
… Eligibility criteria for inclusion in the subcohort were: (a) age 6–11 years at the time of the
visit, with a preference for ages 7–9 years if possible; (b) sufficient stored pregnancy blood and …
visit, with a preference for ages 7–9 years if possible; (b) sufficient stored pregnancy blood and …
[HTML][HTML] Early-life exposome and lung function in children in Europe: an analysis of data from the longitudinal, population-based HELIX cohort
…, B Granum, PK Bird, M Casas, B Oftedal… - The Lancet Planetary …, 2019 - thelancet.com
Background Several single-exposure studies have documented possible effects of environmental
factors on lung function, but none has relied on an exposome approach. We aimed to …
factors on lung function, but none has relied on an exposome approach. We aimed to …
Birth weight, head circumference, and prenatal exposure to acrylamide from maternal diet: the European prospective mother–child study (NewGeneris)
…, S Fleming, E Fthenou, B Granum… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Acrylamide is a common dietary exposure that crosses the human placenta. It
is classified as a probable human carcinogen, and developmental toxicity has been …
is classified as a probable human carcinogen, and developmental toxicity has been …