[HTML][HTML] The effect of current Schistosoma mansoni infection on the immunogenicity of a candidate TB vaccine, MVA85A, in BCG-vaccinated adolescents: An open …
A Wajja, D Kizito, B Nassanga, A Nalwoga… - PLoS neglected …, 2017 - journals.plos.org
Introduction Helminth infection may affect vaccine immunogenicity and efficacy. Adolescents,
a target population for tuberculosis booster vaccines, often have a high helminth burden. …
a target population for tuberculosis booster vaccines, often have a high helminth burden. …
[HTML][HTML] BCG-induced non-specific effects on heterologous infectious disease in Ugandan neonates: an investigator-blind randomised controlled trial
S Prentice, B Nassanga, EL Webb, F Akello… - The Lancet Infectious …, 2021 - thelancet.com
Background Trials done in infants with low birthweight in west Africa suggest that BCG
vaccination reduces all-cause mortality in the neonatal period, probably because of heterologous …
vaccination reduces all-cause mortality in the neonatal period, probably because of heterologous …
Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration
…, CA Figueiredo, SM Langan, B Nassanga… - ERJ open …, 2018 - Eur Respiratory Soc
The World Asthma Phenotypes (WASP) study started in 2016 and has been conducted in five
centres, in the UK, New Zealand, Brazil, Ecuador and Uganda. The objectives of this study …
centres, in the UK, New Zealand, Brazil, Ecuador and Uganda. The objectives of this study …
[HTML][HTML] Safety and immunogenicity of ChAdOx1 85A prime followed by MVA85A boost compared with BCG revaccination among Ugandan adolescents who received …
A Wajja, B Nassanga, A Natukunda… - The Lancet Infectious …, 2024 - thelancet.com
Background BCG confers reduced, variable protection against pulmonary tuberculosis. A
more effective vaccine is needed. We evaluated the safety and immunogenicity of candidate …
more effective vaccine is needed. We evaluated the safety and immunogenicity of candidate …
[HTML][HTML] Effect of Schistosoma mansoni infection and its treatment on antibody responses to measles catch-up immunisation in pre-school children: A randomised trial
R Tweyongyere, BR Nassanga… - PLoS neglected …, 2019 - journals.plos.org
Background Schistosoma infection is associated with immune modulation that can influence
responses to non-schistosome antigens. Vaccine responses may be impaired in S. mansoni…
responses to non-schistosome antigens. Vaccine responses may be impaired in S. mansoni…
A genome‐wide association and replication study of blood pressure in Ugandan early adolescents
…, B Namara, AG Muwenzi, B Nassanga… - Molecular genetics & …, 2019 - Wiley Online Library
Background Genetic association studies of blood pressure (BP) have mostly been conducted
in non‐African populations. Using the Entebbe Mother and Baby Study (EMaBS), we …
in non‐African populations. Using the Entebbe Mother and Baby Study (EMaBS), we …
Optimising the vaccine strategy of BCG, ChAdOx1 85A, and MVA85A for tuberculosis control
A Wajja, B Nassanga, A Natukunda… - The Lancet Infectious …, 2024 - thelancet.com
We write in response to the Comment by Wenping Gong and Jingli Du1 about our published
research article on safety and immunogenicity of ChAdOx1 85A prime followed by MVA85A …
research article on safety and immunogenicity of ChAdOx1 85A prime followed by MVA85A …
[HTML][HTML] Lessons from the first clinical trial of a non-licensed vaccine among Ugandan adolescents: a phase II field trial of the tuberculosis candidate vaccine, MVA85A
…, S Kiwanuka, M Akello, B Nassanga… - Wellcome open …, 2018 - ncbi.nlm.nih.gov
Background: A more effective vaccine for tuberculosis (TB) is a global public health priority.
Vaccines under development will always need evaluation in endemic settings, most of which …
Vaccines under development will always need evaluation in endemic settings, most of which …
Effect of intensive treatment for schistosomiasis on immune responses to vaccines among rural Ugandan island adolescents: randomised controlled trial protocol A for …
G Nkurunungi, L Zirimenya, J Nassuuna… - BMJ open, 2021 - bmjopen.bmj.com
Introduction Several licensed and investigational vaccines have lower efficacy, and induce
impaired immune responses, in low-income versus high-income countries and in rural, …
impaired immune responses, in low-income versus high-income countries and in rural, …
Does Schistosome or Malaria Exposure Contribute to Urban-Rural Differences in Vaccine Responses in Uganda? A Causal Mediation Analysis Using Data from …
…, R Kizindo, R Nkangi, J Kabagenyi, B Nassanga… - papers.ssrn.com
Background: Vaccine immunogenicity and efficacy vary geographically. Chronic immunomodulating
parasitic infections including schistosomes and malaria have been hypothesised to …
parasitic infections including schistosomes and malaria have been hypothesised to …