Human cortical organoids (hCOs), derived from human embryonic stem cells (hESCs),
provide a platform to study human brain development and diseases in complex three-…

Organoid techniques provide unique platforms to model brain development and neurological
disorders. Whereas several methods for recapitulating corticogenesis have been described…

Background Diabetes confers a two times excess risk of cardiovascular disease, yet predicting
individual risk remains challenging. The effect of total microvascular disease burden on …

Human brain organoid techniques have rapidly advanced to facilitate investigating human
brain development and diseases. These efforts have largely focused on generating …

Objective: To provide data regarding the etiology and timing of retrograde type A aortic
dissection (RTAD) after thoracic endovascular aortic repair (TEVAR). Methods: Details of patients …

In soft sediments, Dreissena spp. create firm substrate in the form of aggregates of living
mussels (druses) that roll free on the sediments. Druses provide physical structure which …

Microglia play a role in the emergence and preservation of a healthy brain microenvironment.
Dysfunction of microglia has been associated with neurodevelopmental and …

Background— Endovascular repair of the thoracic aorta has become an increasingly utilized
therapy. Although the short-term mortality advantage over open surgery is well documented…

Objective Thoracic endovascular aortic repair (TEVAR) of various pathologies has been
associated with peri-interventional neurologic complication rates of up to 15%. The objective of …

Aortic dissection is caused by an intimal and medial tear in the aorta with propagation of a
false lumen within the aortic media. It is part of the “acute aortic syndrome”—an umbrella term …