User profiles for Clare Lendrem
Beverley Clare LendremStatistical Methodologist, Newcastle University Verified email at newcastle.ac.uk Cited by 1367 |
First experience of COVID-19 screening of health-care workers in England
Since March 10, 2020, the Newcastle upon Tyne Hospitals National Health Service (NHS)
Foundation Trust has been screening symptomatic health-care workers for severe acute …
Foundation Trust has been screening symptomatic health-care workers for severe acute …
IL-12, IL-15, and IL-18 pre-activated NK cells target resistant T cell acute lymphoblastic leukemia and delay leukemia development in vivo
M Boieri, A Ulvmoen, A Sudworth, C Lendrem… - …, 2017 - Taylor & Francis
NK cells have shown promise in therapy of hematological cancers, in particular against acute
myeloid leukemia. In contrast, the more NK cell-resistant acute lymphoblastic leukemia (…
myeloid leukemia. In contrast, the more NK cell-resistant acute lymphoblastic leukemia (…
[HTML][HTML] COVID-19 management in a UK NHS foundation trust with a high consequence infectious diseases centre: A retrospective analysis
…, N Alderson, C Lendrem, DW Lendrem… - Medical …, 2021 - mdpi.com
Recent large national and international cohorts describe the baseline characteristics and
outcome of hospitalised patients with COVID-19, however there is limited granularity to these …
outcome of hospitalised patients with COVID-19, however there is limited granularity to these …
[HTML][HTML] Serum and extracellular vesicle microRNAs miR-423, miR-199, and miR-93* as biomarkers for acute graft-versus-host disease
…, M Kralj Juric, KF Pearce, C Lendrem… - Frontiers in …, 2017 - frontiersin.org
Acute graft-versus-host disease (aGvHD) is a major cause of adverse outcome in hematopoietic
stem cell transplantation (HSCT), with a high incidence (20–50%). A novel, non-invasive …
stem cell transplantation (HSCT), with a high incidence (20–50%). A novel, non-invasive …
Why is it hard to terminate failing projects in pharmaceutical R&D?
RW Peck, DW Lendrem, I Grant, BC Lendrem… - Nature reviews Drug …, 2015 - nature.com
Abstract'Quick-kill'strategies in pharmaceutical research and development aim to reduce late-
stage attrition by bringing project termination decisions forward, to an earlier point in the …
stage attrition by bringing project termination decisions forward, to an earlier point in the …
[HTML][HTML] Genome-wide association study identifies susceptibility loci for acute myeloid leukemia
…, AM Dickinson, E Douglas, C Lendrem… - Nature …, 2021 - nature.com
Acute myeloid leukemia (AML) is a hematological malignancy with an undefined heritable
risk. Here we perform a meta-analysis of three genome-wide association studies, with …
risk. Here we perform a meta-analysis of three genome-wide association studies, with …
[HTML][HTML] Expression of serum microRNAs is altered during acute graft-versus-host disease
Acute graft-versus-host disease (aGvHD) is the most frequent and serious complication
following hematopoietic stem cell transplantation (HSCT), with a high mortality rate. A clearer …
following hematopoietic stem cell transplantation (HSCT), with a high mortality rate. A clearer …
[HTML][HTML] COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study
Background A subset of patients with severe COVID-19 develop a hyperinflammatory
syndrome, which might contribute to morbidity and mortality. This study explores a specific …
syndrome, which might contribute to morbidity and mortality. This study explores a specific …
[HTML][HTML] Systematic review of studies investigating ventilator associated pneumonia diagnostics in intensive care
Background Ventilator-associated pneumonia (VAP) is an important diagnosis in critical
care. VAP research is complicated by the lack of agreed diagnostic criteria and reference …
care. VAP research is complicated by the lack of agreed diagnostic criteria and reference …
[HTML][HTML] miR-146a and miR-155 expression levels in acute graft-versus-host disease incidence
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment for
numerous hematological malignancies. However, acute graft-versus-host disease (aGVHD) is …
numerous hematological malignancies. However, acute graft-versus-host disease (aGVHD) is …