The diagnosis of primary ciliary dyskinesia is often confirmed with standard, albeit complex
and expensive, tests. In many cases, however, the diagnosis remains difficult despite the …

Background Preterm birth, low birth weight, and infant catch-up growth seem associated
with an increased risk of respiratory diseases in later life, but individual studies showed …

Primary ciliary dyskinesia (PCD) is a hereditary disorder of mucociliary clearance causing
chronic upper and lower airways disease. We determined the number of patients with …

Motile cilia are highly complex hair-like organelles of epithelial cells lining the surface of
various organ systems. Genetic mutations (usually with autosomal recessive inheritance) that …

Asthma and wheezing disorders are common chronic health problems in childhood. Breastfeeding
provides health benefits, but it is not known whether or how breastfeeding decreases …

Background Medulloblastoma is associated with rare hereditary cancer predisposition
syndromes; however, consensus medulloblastoma predisposition genes have not been defined …

Rationale: The current hypothesis that human pulmonary alveolarization is complete by 3
years is contradicted by new evidence of alveolarization throughout adolescence in mammals. …

Background Diagnosing asthma in children represents an important clinical challenge. There
is no single gold-standard test to confirm the diagnosis. Consequently, over- and under-…

Background It has been hypothesized that children and adolescents might be more vulnerable
to possible health effects from mobile phone exposure than adults. We investigated …

Since the publication of the European Respiratory Society Task Force report in 2008, significant
new evidence has become available on the classification and management of preschool …