Bronchopulmonary dysplasia (BPD) frequently complicates preterm birth and leads to
significant long-term morbidity. Unfortunately, few therapies are known to effectively prevent or …

In infants intolerant of enteral feeding because of intestinal disease, parenteral nutrition may
be associated with cholestasis, which can progress to end-stage liver disease. Here we …

Objective To provide the best clinical practice guidance for surfactant use in preterm
neonates with respiratory distress syndrome (RDS). The RDS-Neonatal Expert Taskforce (RDS-…

Aims: The response to oxidative stress and inflammation varies with diurnal rhythms. Nevertheless,
it is not known whether circadian genes are regulated by these stimuli. We evaluated …

Background The ideal threshold at which surfactant administration in preterm neonates with
respiratory distress syndrome (RDS) is most beneficial is contentious. The aim of this …

Hepatic innate immune function plays an important role in the pathogenesis of many diseases.
Importantly, a growing body of literature has firmly established the spatial heterogeneity …

Bronchopulmonary dysplasia (BPD) is among the most common and severe sequelae of
extreme preterm birth. 1, 2 Since the initial descriptions of the disease more than 50 years ago, …

Supporting the respiratory status of the newly born, criti-cally ill premature neonate is a long
held focus of the practicing neonatologist. One could argue that neonatology evolved out of …

The need to identify safe and effective interventions to prevent bronchopulmonary dysplasia
(BPD) has reached a critical point. In the simplest terms, BPD is the most common morbidity …

For nearly 100 y, pediatricians have regularly used oxygen to treat neonatal and childhood
diseases. During this time, it has become clear that oxygen is toxic and that overzealous use …