User profiles for Colin Church
Colin ChurchUniversity of Glasgow Verified email at glasgow.ac.uk Cited by 1783 |
[HTML][HTML] Perioperative management of patients with pulmonary hypertension undergoing non-cardiothoracic, non-obstetric surgery: a systematic review and expert …
Background The risk of complications, including death, is substantially increased in patients
with pulmonary hypertension (PH) undergoing anaesthesia for surgical procedures, …
with pulmonary hypertension (PH) undergoing anaesthesia for surgical procedures, …
The chief scientist office cardiovascular and pulmonary imaging in SARS coronavirus disease-19 (CISCO-19) study
Background COVID-19 is typically a primary respiratory illness with multisystem involvement.
The prevalence and clinical significance of cardiovascular and multisystem involvement in …
The prevalence and clinical significance of cardiovascular and multisystem involvement in …
[PDF][PDF] Comprehensive rare variant analysis via whole-genome sequencing to determine the molecular pathology of inherited retinal disease
…, E Chalmers, A Chandra, P Chinnery, C Church… - The American Journal of …, 2017 - cell.com
Inherited retinal disease is a common cause of visual impairment and represents a highly
heterogeneous group of conditions. Here, we present findings from a cohort of 722 individuals …
heterogeneous group of conditions. Here, we present findings from a cohort of 722 individuals …
[HTML][HTML] Identification of rare sequence variation underlying heritable pulmonary arterial hypertension
…, S Holden, M Aldred, HJ Bogaard, C Church… - Nature …, 2018 - nature.com
Pulmonary arterial hypertension (PAH) is a rare disorder with a poor prognosis. Deleterious
variation within components of the transforming growth factor-β pathway, particularly the …
variation within components of the transforming growth factor-β pathway, particularly the …
[HTML][HTML] A multisystem, cardio-renal investigation of post-COVID-19 illness
The pathophysiology and trajectory of post-Coronavirus Disease 2019 (COVID-19) syndrome
is uncertain. To clarify multisystem involvement, we undertook a prospective cohort study …
is uncertain. To clarify multisystem involvement, we undertook a prospective cohort study …
[HTML][HTML] Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis
Background Rare genetic variants cause pulmonary arterial hypertension, but the contribution
of common genetic variation to disease risk and natural history is poorly characterised. …
of common genetic variation to disease risk and natural history is poorly characterised. …
Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension
…, J Martin, C Treacy, K Yates, H Bogaard, C Church… - Circulation, 2017 - Am Heart Assoc
Background: Pulmonary arterial hypertension (PAH) is a rare disease with an emerging
genetic basis. Heterozygous mutations in the gene encoding the bone morphogenetic protein …
genetic basis. Heterozygous mutations in the gene encoding the bone morphogenetic protein …
[HTML][HTML] Thromboembolic risk in hospitalized and nonhospitalized COVID-19 patients: a self-controlled case series analysis of a nationwide cohort
Objective To assess the associations between coronavirus disease 2019 (COVID-19) infection
and thromboembolism including myocardial infarction (MI), ischemic stroke, deep vein …
and thromboembolism including myocardial infarction (MI), ischemic stroke, deep vein …
Nuclear IL-33 regulates soluble ST2 receptor and IL-6 expression in primary human arterial endothelial cells and is decreased in idiopathic pulmonary arterial …
…, C Meng, P Dormuller, PC Chou, C Church… - Biochemical and …, 2014 - Elsevier
Idiopathic pulmonary arterial hypertension (IPAH) is an incurable condition leading to right
ventricular failure and death and inflammation is postulated to be associated with vascular …
ventricular failure and death and inflammation is postulated to be associated with vascular …
Characterization of GDF2 Mutations and Levels of BMP9 and BMP10 in Pulmonary Arterial Hypertension
…, S Holden, HJ Bogaard, C Church… - American journal of …, 2020 - atsjournals.org
Rationale: Recently, rare heterozygous mutations in GDF2 were identified in patients with
pulmonary arterial hypertension (PAH). GDF2 encodes the circulating BMP (bone …
pulmonary arterial hypertension (PAH). GDF2 encodes the circulating BMP (bone …