User profiles for Daniel Navajas
Daniel NavajasProfessor Emeritus of Physiology, School of Medicine and Health Sciences. University of … Verified email at ub.edu Cited by 51386 |
Biophysically preconditioning mesenchymal stem cells improves treatment of ventilator-induced lung injury
…, A Artigas, I Almendros, D Navajas - Archivos de …, 2020 - pubmed.ncbi.nlm.nih.gov
… 4 , Daniel Navajas …
Universal physical responses to stretch in the living cell
With every beat of the heart, inflation of the lung or peristalsis of the gut, cell types of diverse
function are subjected to substantial stretch. Stretch is a potent stimulus for growth, …
function are subjected to substantial stretch. Stretch is a potent stimulus for growth, …
Scaling the microrheology of living cells
We report a scaling law that governs both the elastic and frictional properties of a wide
variety of living cell types, over a wide range of time scales and under a variety of biological …
variety of living cell types, over a wide range of time scales and under a variety of biological …
[PDF][PDF] Force triggers YAP nuclear entry by regulating transport across nuclear pores
YAP is a mechanosensitive transcriptional activator with a critical role in cancer, regeneration,
and organ size control. Here, we show that force applied to the nucleus directly drives …
and organ size control. Here, we show that force applied to the nucleus directly drives …
[HTML][HTML] Microrheology of human lung epithelial cells measured by atomic force microscopy
Lung epithelial cells are subjected to large cyclic forces from breathing. However, their response
to dynamic stresses is poorly defined. We measured the complex shear modulus (G * (ω…
to dynamic stresses is poorly defined. We measured the complex shear modulus (G * (ω…
Collective cell durotaxis emerges from long-range intercellular force transmission
The ability of cells to follow gradients of extracellular matrix stiffness—durotaxis—has been
implicated in development, fibrosis, and cancer. Here, we found multicellular clusters that …
implicated in development, fibrosis, and cancer. Here, we found multicellular clusters that …
Probing mechanical properties of living cells by atomic force microscopy with blunted pyramidal cantilever tips
Atomic force microscopy (AFM) allows the acquisition of high-resolution images and the
measurement of mechanical properties of living cells under physiological conditions. AFM …
measurement of mechanical properties of living cells under physiological conditions. AFM …
Time scale and other invariants of integrative mechanical behavior in living cells
In dealing with systems as complex as the cytoskeleton, we need organizing principles or,
short of that, an empirical framework into which these systems fit. We report here unexpected …
short of that, an empirical framework into which these systems fit. We report here unexpected …
Effectiveness of CPAP treatment in daytime function in sleep apnea syndrome: a randomized controlled study with an optimized placebo
Application of continuous positive airway pressure (CPAP) as the standard treatment for
sleep apnea/hypopnea syndrome (SAHS) is a moot point. Studies on the effectiveness of this …
sleep apnea/hypopnea syndrome (SAHS) is a moot point. Studies on the effectiveness of this …
Force loading explains spatial sensing of ligands by cells
…, I Platzman, P Delcanale, L Albertazzi, D Navajas… - Nature, 2017 - nature.com
Cells can sense the density and distribution of extracellular matrix (ECM) molecules by means
of individual integrin proteins and larger, integrin-containing adhesion complexes within …
of individual integrin proteins and larger, integrin-containing adhesion complexes within …