Obstructive sleep apnea (OSA) is associated with repetitive nocturnal arterial oxygen
desaturation and hypercapnia, large intrathoracic negative pressure swings, and acute increases …

Group 3 pulmonary hypertension (PH) is a common complication of chronic lung disease (CLD),
including chronic obstructive pulmonary disease (COPD), interstitial lung disease, and …

Daytime pulmonary hypertension (PH) is relatively common in obstructive sleep apnea (OSA)
and is thought to be associated with pulmonary vascular remodeling (PRm). The extent to …

To determine whether pulmonary hypertension (PH) can occur in obstructive sleep apnea
syndrome (OSAS) in the absence of lung or primary cardiac disease, we studied 27 patients (…

Background Patients with chronic obstructive pulmonary disease (COPD) can be classified
into groups A/C or B/D based on symptom intensity. Different threshold values for symptom …

Background Benralizumab is an interleukin-5 receptor α-directed cytolytic monoclonal
antibody that has been shown to safely reduce exacerbations and improve lung function for …

Changes in sleep posture have been shown to improve obstructive sleep apnea (OSA). To
investigate the mechanisms by which this occurs we assessed upper airway stability in eight …

It is controversial whether obstructive sleep apnea (OSA) causes pulmonary hypertension (PH)
in the absence of hypoxemic lung disease. To investigate this further we measured …

We evaluated the predictive value of the COPD assessment test (CAT™) for exacerbation in
the following six months or time to first exacerbation among COPD patients with previous …

BACKGROUND: Timely vaccine supply is critical during influenza pandemics. A
recombinant hemagglutinin (rHA)-based vaccine could overcome production hurdles of egg-based …