Rationale: Patients with chronic obstructive pulmonary disease (COPD) are susceptible to
respiratory viral infections that cause exacerbations. The mechanisms underlying this …

Rationale: Viral infections are major drivers of exacerbations and clinical burden in patients
with asthma and chronic obstructive pulmonary disease (COPD). IFN-β is a key component …

Objectives Rapid, high throughput diagnostics are a valuable tool, allowing the detection of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in populations so as to …

Background Small airways disease (SAD) is a key component of COPD and is a main
contributing factor to lung function decline. Research Question Is SAD a key feature of frequent …

Background Chronic obstructive pulmonary disease (COPD) patients are at increased risk
of poor outcome from Coronavirus disease (COVID-19). Early data suggest elevated Severe …

Rationale Pulmonary surfactant is vital for lung homeostasis as it reduces surface tension to
prevent alveolar collapse and provides essential immune-regulatory and antipathogenic …

The asthmatic lung is prone to respiratory viral infections that exacerbate the symptoms of
the underlying disease. Recent work has suggested that a deficient T-helper cell type 1 …

Redox dysregulation and oxidative stress have been implicated in asthma pathogenesis.
Exercise interventions improve symptoms and reduce inflammation in asthma patients, but the …

Introduction Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition
without effective disease modifying therapies. Identification of novel inflammatory endotype …

We have developed a simple and inexpensive device to obtain linear sucrose gradients
with commonly used laboratory materials—a syringe, a flask, a plastic tube, and a piece of …