Amiodarone: review of pulmonary effects and toxicity

…, C Triantafillidou, L Kolilekas, D Markoulaki, ED Manali - Drug safety, 2010 - Springer
Amiodarone, a bi-iodinated benzofuran derivative, is, because of its high effectiveness, one
of the most widely used antiarrhythmic agents. However, adverse effects, especially …

[HTML][HTML] Bench-to-bedside review: Pulmonary–renal syndromes–an update for the intensivist

SA Papiris, ED Manali, I Kalomenidis, GE Kapotsis… - Critical Care, 2007 - Springer
The term Pulmonary–renal syndrome refers to the combination of diffuse alveolar haemorrhage
and rapidly progressive glomerulonephritis. A variety of mechanisms such as those …

[HTML][HTML] Idiopathic pulmonary fibrosis: best practice in monitoring and managing a relentless fibrotic disease

…, O Hilberg, J Magnusson, ED Manali… - Respiration, 2020 - karger.com
Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial lung disease that is, by definition,
progressive. Progression of IPF is reflected by a decline in lung function, worsening of …

[HTML][HTML] MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease

…, E Ambrocio-Ortiz, E Manali… - … England Journal of …, 2018 - Mass Medical Soc
Background Given the phenotypic similarities between rheumatoid arthritis (RA)–associated
interstitial lung disease (ILD) (hereafter, RA-ILD) and idiopathic pulmonary fibrosis, we …

High levels of IL-6 and IL-8 characterize early-on idiopathic pulmonary fibrosis acute exacerbations

…, K Kagouridis, S Loukides, P Karakitsos, ED Manali - Cytokine, 2018 - Elsevier
Introduction Controversy exists about the pathogenesis of idiopathic pulmonary fibrosis acute
exacerbations (IPF-AEs). According to one hypothesis IPF-AEs represent the development …

Sleep oxygen desaturation predicts survival in idiopathic pulmonary fibrosis

L Kolilekas, E Manali, KA Vlami… - Journal of Clinical …, 2013 - jcsm.aasm.org
Background: Recent studies suggest poor sleep quality in patients with idiopathic pulmonary
fibrosis (IPF). However, so far, the impact of IPF-related sleep breathing disorders (SBDs) …

[HTML][HTML] MRC chronic Dyspnea Scale: Relationships with cardiopulmonary exercise testing and 6-minute walk test in idiopathic pulmonary fibrosis patients: a …

ED Manali, P Lyberopoulos, C Triantafillidou… - BMC pulmonary …, 2010 - Springer
Background Exertional dyspnea is the most prominent and disabling feature in idiopathic
pulmonary fibrosis (IPF). The Medical Research Chronic (MRC) chronic dyspnea score as well …

[HTML][HTML] Survival in idiopathic pulmonary fibrosis acute exacerbations: the non-steroid approach

…, A Kotanidou, A Karakatsani, ED Manali - BMC pulmonary …, 2015 - Springer
Background Idiopathic pulmonary fibrosis acute exacerbation (IPF-AE) constitutes IPF’s
most devastating event, representing the unexpected superimposition of diffuse alveolar …

[HTML][HTML] The Medical Research Council chronic dyspnea score predicts the survival of patients with idiopathic pulmonary fibrosis

ED Manali, GT Stathopoulos, A Kollintza… - Respiratory …, 2008 - Elsevier
BACKGROUND: The Medical Research Council (MRC) chronic dyspnea scale (6-point) is
used in different clinical conditions to grade breathlessness on daily activities. We have …

[HTML][HTML] Expression of PD-1/PD-L1 axis in mediastinal lymph nodes and lung tissue of human and experimental lung fibrosis indicates a potential therapeutic target for …

…, M Katsaras, F Sampsonas, K Dimakou, ED Manali… - Respiratory …, 2023 - Springer
Background Mediastinal lymph node enlargement is prevalent in patients with idiopathic
pulmonary fibrosis (IPF). Studies investigating whether this phenomenon reflects specific …