Rationale Individuals exposed to second-hand smoking may be more susceptible to asthma
and chronic obstructive pulmonary disease (COPD). We investigated the risk of respiratory …

Background Randomised controlled trials found that low-density lipoprotein (LDL)
cholesterol-lowering statins increase lung function and possibly decrease rate of exacerbations in …

Background Individuals with α 1 -antitrypsin deficiency have increased elastase activity
resulting in continuous degradation of elastin and early onset of COPD. Increased elastase …

Background Chronic cough affects up to 10% of the general population and was previously
perceived as a comorbidity of underlying conditions, but is nowadays classified as a disease …

Individuals with severe α1-antitrypsin deficiency have increased elastase activity causing
continuous degradation of elastin resulting in an early onset of COPD. It has been suggested, …

Background Obese individuals may be at higher risk of chronic cough. We investigated the
risk and impact of chronic cough in obese individuals from the general population. Methods …

Background Several risk factors for asthma have been proposed; however, the causality of
these associations is sometimes unclear. Mendelian randomization is a powerful …

Background Increased elastase activity in α 1 -antitrypsin deficiency may affect elasticity of
the arterial walls, and thereby blood pressure and susceptibility to cardiovascular disease. …

… KF Nilausen, EM Landt and M. Dahl wrote the draft manuscript and performed the statistical
analyses. All authors were involved in revising the manuscript for important intellectual …

… EM Landt received the ERS grant for best abstract in “Chronic Cough” 2022, outside the
submitted work. SJH Vijverberg has received grants or contracts from Lung Foundation …