In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered the …

Rationale: Oxidative stress is involved in the skeletal muscle dysfunction observed in patients
with severe chronic obstructive pulmonary disease (COPD). We hypothesized that the …

Background: Limb muscle dysfunction is prevalent in chronic obstructive pulmonary disease
(COPD) and it has important clinical implications, such as reduced exercise tolerance, …

The views and recommendations made in this document do not represent the official position
of any publisher or professional medical society. This document has not been endorsed by …

Assessing respiratory mechanics and muscle function is critical for both clinical practice and
research purposes. Several methodological developments over the past two decades have …

The present study was aimed at evaluating the effects of a specific inspiratory muscle
training protocol on the structure of inspiratory muscles in patients with chronic obstructive …

Rationale: Inflammation and oxidative stress contribute to muscle dysfunction in patients
with chronic obstructive pulmonary disease (COPD). Oxidants contained in cigarette smoke (CS…

Prediction models aim to use available data to predict a health state or outcome that has not
yet been observed. Prediction is primarily relevant to clinical practice, but is also used in …

The maintenance of mitochondrial integrity is critical for muscle health. Mitochondria, indeed,
play vital roles in a wide range of cellular processes, including energy supply, Ca 2+ …

Skeletal muscle dysfunction occurs in patients with chronic obstructive pulmonary disease (COPD)
and affects both ventilatory and nonventilatory muscle groups. It represents a very …