Reduced lung elastic recoil and fixed airflow obstruction in asthma

…, BG Oliver, SC Zimmermann, S Milne, F Sanai… - …, 2020 - Wiley Online Library
Background and objective Fixed airflow obstruction (FAO) in asthma occurs despite optimal
inhaled treatment and no smoking history, and remains a significant problem, particularly …

Evaluation of a continuous blood glucose monitor: a novel and non-invasive wearable using bioimpedance technology

F Sanai, AS Sahid, J Huvanandana… - Journal of Diabetes …, 2023 - journals.sagepub.com
Background: Frequent blood glucose level (BGL) monitoring is essential for effective
diabetes management. Poor compliance is common due to the painful finger pricking or …

Within-session variability as quality control for oscillometry in health and disease

LM Harkness, K Patel, F Sanai, S Rutting… - ERJ Open …, 2021 - Eur Respiratory Soc
Oscillometry is increasingly adopted in respiratory clinics, but many recommendations regarding
measurement settings and quality control remain subjective. The aim of this study was …

Higher body mass index is associated with increased lung stiffness and less airway obstruction in individuals with asthma and fixed airflow obstruction

S Rutting, DG Chapman, T Badal, F Sanai… - ERJ Open …, 2021 - Eur Respiratory Soc
Persistent or fixed airflow obstruction (FAO) is prevalent in up to 60% of patients with severe
asthma [1] and is associated with older age, more rapid decline in lung function and …

What is the “Areca” in “Areca nuts”? Extraction and neuroactive bioassay of arecoline

K Locock, T Bakas, F Sanai, R Allan… - Journal of Chemical …, 2016 - ACS Publications
A series of three practical sessions are designed to give students firsthand experience with
the preparation of natural product extracts and assay using a live tissue preparation. Areca or …

Relationship between pre-bronchodilator FEV1 and ex-vivo intrinsic tone in human small airways

F Sanai, A Cairncross, PB Noble, JG Elliot, AL James… - 2019 - Eur Respiratory Soc
Introduction: Narrowing of small airways in COPD and asthma may contribute to
hyperresponsiveness for which the mechanisms are unknown. This study explored the contractility of …

Intrinsic tone in human airway smooth muscle increases subsequent contractile response

A Cairncross, F Sanai, B Mcparland, G King, P Mcfawn… - 2018 - Eur Respiratory Soc
Introduction: Small airway abnormalities are implicated as a primary cause of functional
impairment in obstructive airway disease. Contraction of the airway smooth muscle (ASM) layer …

Elevers föreställningar om liv: undersökning av elevers lärande ur ett socialkonstruktivistiskt perspektiv

J Persson, P Sanai-Farid - 2013 - diva-portal.org
The purpose with this study was to analyse students' conception of living things, and to
establish how a social constructivist learning situation affect their conceptions. The method …

Distensibility of Human Small Airways Is Reduced by Intrinsic Smooth Muscle Tone

F Sanai, A Cairncross, JG Elliot, PB Noble… - B20. ASTHMA: NEW …, 2018 - atsjournals.org
Rationale: Distensibility depends on smooth muscle tone and tissue structural stiffness.
Human large airways (3-12mm internal diameter) in vitro exhibit considerable intrinsic smooth …

Potential Differences in Calcium Sensitization Driving Human Small Airway Smooth Muscle Contractility in Obstructive Disease

F Sanai, A Cairncross, PB Noble, JG Elliot… - … : FROM CELL TO …, 2019 - atsjournals.org
Rationale: The mechanisms for airway hyperresponsiveness in asthma and COPD are
unknown. Narrowing of the small airways in these diseases is thought to have a major …