Endothelin-1 Increases Vascular Superoxide via EndothelinA–NADPH Oxidase Pathway in Low-Renin Hypertension
L Li, GD Fink, SW Watts, CA Northcott, JJ Galligan… - Circulation, 2003 - Am Heart Assoc
Background— Angiotensin II–induced hypertension is associated with NAD(P)H oxidase–dependent
superoxide production in the vessel wall. Vascular superoxide level is also …
superoxide production in the vessel wall. Vascular superoxide level is also …
Tissue-Specific cytokine production during experimental acute pancreatitis (a probable mechanism for distant organ dysfunction)
JG Norman, GW Fink, W Denham, J Yang… - Digestive diseases and …, 1997 - Springer
Our purpose was to determine if cytokines are produced systemically during acute
pancreatitis. Proinflammatory cytokines are elevated during acute pancreatitis and have been …
pancreatitis. Proinflammatory cytokines are elevated during acute pancreatitis and have been …
Acute pancreatitis induces intrapancreatic tumor necrosis factor gene expression
JG Norman, GW Fink, MG Franz - Archives of surgery, 1995 - jamanetwork.com
Objective: To examine the intrapancreatic production of tumor necrosis factor (TNF) α and
define its cell of origin during acute pancreatitis. Design: Acute necrotizing pancreatitis was …
define its cell of origin during acute pancreatitis. Design: Acute necrotizing pancreatitis was …
Circulating angiotensin II and dietary salt: converging signals for neurogenic hypertension
JW Osborn, GD Fink, AF Sved, GM Toney… - Current hypertension …, 2007 - Springer
Circulating angiotensin II (Ang II) combined with high salt intake increases sympathetic nerve
activity (SNA) in some forms of hypertension. Ang II-induced increases in SNA are modest, …
activity (SNA) in some forms of hypertension. Ang II-induced increases in SNA are modest, …
Chemerin connects fat to arterial contraction
…, JM Thompson, R Burnett, GD Fink - … , and vascular biology, 2013 - Am Heart Assoc
Objective— Obesity and hypertension are comorbid in epidemic proportion, yet their biological
connection is largely a mystery. The peptide chemerin is a candidate for connecting fat …
connection is largely a mystery. The peptide chemerin is a candidate for connecting fat …
Splanchnic circulation is a critical neural target in angiotensin II salt hypertension in rats
AJ King, JW Osborn, GD Fink - Hypertension, 2007 - Am Heart Assoc
Chronic angiotensin II (Ang II) infusion, in rats fed high salt, engages the sympathetic nervous
system to increase venomotor tone. The splanchnic sympathetic nervous system is the …
system to increase venomotor tone. The splanchnic sympathetic nervous system is the …
A novel method of selective ablation of afferent renal nerves by periaxonal application of capsaicin
…, RD Wainford, WC Engeland, GD Fink… - American Journal …, 2015 - journals.physiology.org
Renal denervation has been shown to lower arterial pressure in some hypertensive patients,
yet it remains unclear whether this is due to ablation of afferent or efferent renal nerves. To …
yet it remains unclear whether this is due to ablation of afferent or efferent renal nerves. To …
Area postrema is critical for angiotensin-induced hypertension in rats.
GD Fink, CA Bruner, ML Mangiapane - Hypertension, 1987 - Am Heart Assoc
The effect of surgical ablation of the area postrema on acute (5-10 minutes) and chronic (5-10
days) increases in mean arterial pressure produced by intravenous infusion of angiotensin …
days) increases in mean arterial pressure produced by intravenous infusion of angiotensin …
Left versus right atrial difference in dominant frequency, K+ channel transcripts, and fibrosis in patients developing atrial fibrillation after cardiac surgery
MF Swartz, GW Fink, CJ Lutz, SM Taffet, O Berenfeld… - Heart rhythm, 2009 - Elsevier
BACKGROUND: The development of atrial fibrillation (AF) after cardiac surgery is associated
with adverse outcomes; however, the mechanism(s) that trigger and maintain AF in these …
with adverse outcomes; however, the mechanism(s) that trigger and maintain AF in these …
Decreased mortality of severe acute pancreatitis after proximal cytokine blockade.
JG Norman, MG Franz, GS Fink, J Messina… - Annals of …, 1995 - ncbi.nlm.nih.gov
OBJECTIVE: This study determined the ability of interleukin-1 receptor antagonist (IL-1ra) to
decrease the mortality of experimental acute pancreatitis. The response of the inflammatory …
decrease the mortality of experimental acute pancreatitis. The response of the inflammatory …