[HTML][HTML] Recommendations for intensive care unit and hospital preparations for an influenza epidemic or mass disaster: summary report of the European Society of …

…, GM Joynt, JL Hick, B Taylor, GA Richards… - Intensive care …, 2010 - Springer
Purpose To provide recommendations and standard operating procedures for intensive care
units and hospital preparedness for an influenza pandemic. Methods Based on a literature …

How the genetics of deafness illuminates auditory physiology

GP Richardson, JB de Monvel… - Annual review of …, 2011 - annualreviews.org
Although the basic principles underlying the function of the peripheral auditory system have
been known for many years, the molecules required for hearing have hitherto remained …

Linking genes underlying deafness to hair-bundle development and function

C Petit, GP Richardson - Nature neuroscience, 2009 - nature.com
The identification of mutations underlying monogenic, early-onset forms of deafness in
humans has provided unprecedented insight into the molecular mechanisms of hearing in the …

[HTML][HTML] Effect of recombinant surfactant protein C–based surfactant on the acute respiratory distress syndrome

…, PF Laterre, MC Witte, GA Richards… - … England Journal of …, 2004 - Mass Medical Soc
Background Preclinical studies suggest that exogenous surfactant may be of value in the
treatment of the acute respiratory distress syndrome (ARDS), and two phase 2 clinical trials …

Antimicrobial stewardship across 47 South African hospitals: an implementation study

…, AP Messina, C Feldman, GA Richards… - The Lancet Infectious …, 2016 - thelancet.com
Background The available data on antimicrobial stewardship programmes in Africa are scarce.
The aims of this study were to assess the implementation of an antimicrobial stewardship …

FM1-43 dye behaves as a permeant blocker of the hair-cell mechanotransducer channel

…, HJ Kennedy, CJ Kros, GP Richardson - Journal of …, 2001 - Soc Neuroscience
Hair cells in mouse cochlear cultures are selectively labeled by brief exposure to FM1-43, a
styryl dye used to study endocytosis and exocytosis. Real-time confocal microscopy …

Mutations in the human α-tectorin gene cause autosomal dominant non-syndromic hearing impairment

…, T Somers, FE Offeciers, PV Heyning, GP Richardson… - Nature …, 1998 - nature.com
The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia
bundles of specialized sensory hair cells. Sound induces movement of these hair cells …

[HTML][HTML] Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR …

…, H Akatsuka, T Sato, T Aida, R Redder, GP Richardson… - Genome biology, 2017 - Springer
Background Conditional knockout mice and transgenic mice expressing recombinases,
reporters, and inducible transcriptional activators are key for many genetic studies and comprise …

Nonsyndromic hearing impairment is associated with a mutation in DFNA5

…, RJH Smith, PJ Willems, PK Legan, GP Richardson… - Nature …, 1998 - nature.com
Nonsyndromic hearing impairment is one of the most heterogeneous hereditary conditions,
with more than 40 loci mapped on the human genome 1, however, only a limited number of …

[HTML][HTML] A targeted deletion in α-tectorin reveals that the tectorial membrane is required for the gain and timing of cochlear feedback

…, RJ Goodyear, M Kössl, IJ Russell, GP Richardson - Neuron, 2000 - cell.com
α-tectorin is an extracellular matrix molecule of the inner ear. Mice homozygous for a
targeted deletion in α-tectorin have tectorial membranes that are detached from the cochlear …