Bronchoconstriction due to cold weather in COPD: the roles of direct airway effects and cutaneous reflex mechanisms

HO Koskela, HO Tukiainen, AK Koskela - Chest, 1996 - Elsevier
To clarify how cold weather may induce bronchoconstriction in patients with COPD, a series
of challenges were performed in 20 patients with COPD in stable condition as well as in 13 …

Defining the risk factors for acute, subacute and chronic cough: a cross-sectional study in a Finnish adult employee population

AM Lätti, J Pekkanen, HO Koskela - BMJ open, 2018 - bmjopen.bmj.com
Objectives Chronic cough is linked to various long-standing risk factors like asthma, chronic
rhinitis and oesophageal reflux disease. On the contrary, acute and subacute cough are …

Coughing during mannitol challenge is associated with asthma

HO Koskela, L Hyvärinen, JD Brannan, HK Chan… - Chest, 2004 - Elsevier
… Author links open overlay panel Heikki O. Koskela MD a , Liisa Hyvärinen MD a , John D.
Brannan PhD b , Hak-Kim Chan PhD c , … H Koskela, MB Di Sciascio, SD Anderson, et al. …

[HTML][HTML] Long-term prognosis of chronic cough: a prospective, observational cohort study

HO Koskela, AM Lätti, MK Purokivi - BMC Pulmonary Medicine, 2017 - Springer
Background The long-term prognosis of chronic cough and its determinants need to be
clarified. Methods This is a prospective, observational cohort study. Eighty-nine unselected …

[HTML][HTML] The impacts of cough: a cross-sectional study in a Finnish adult employee population

HO Koskela, AM Lätti, J Pekkanen - ERJ Open Research, 2018 - Eur Respiratory Soc
Given the very high prevalence of cough, little is known about its impacts. A questionnaire
was sent via e-mail to all public service employees in two towns in Finland. There were 373 …

Sensitivity and validity of three bronchial provocation tests to demonstrate the effect of inhaled corticosteroids in asthma

HO Koskela, L Hyva, JD Brannan, HK Chan… - Chest, 2003 - Elsevier
Study objectives To compare the sensitivity and validity of mannitol, histamine, and cold air
challenges to demonstrate the effect of inhaled corticosteroids (ICS) in asthma. Design A …

Long-term mortality after community-acquired pneumonia—impacts of diabetes and newly discovered hyperglycaemia: a prospective, observational cohort study

HO Koskela, PH Salonen, J Romppanen… - BMJ open, 2014 - bmjopen.bmj.com
Objectives Community-acquired pneumonia is associated with a significant long-term
mortality after initial recovery. It has been acknowledged that additional research is urgently …

Cough as an adverse effect on inhalation pharmaceutical products

…, JD Brannan, HO Koskela… - British Journal of …, 2020 - Wiley Online Library
Cough is an adverse effect that may hinder the delivery of drugs into the lungs. Chemical or
mechanical stimulants activate the transient receptor potential in some airway afferent …

Responsiveness to three bronchial provocation tests in patients with asthma

HO Koskela, L Hyva, JD Brannan, HK Chan… - Chest, 2003 - Elsevier
… Author links open overlay panel Heikki O. Koskela MD a , Liisa Hyvarinen MD a , John D.
Brannan PhD b , Hak-Kim Chan PhD c , Sandra D. … HO Koskela, SH Rasanen, HO Tukiainen …

Hyperglycaemia during exacerbations of asthma and chronic obstructive pulmonary disease

HO Koskela, PH Salonen… - The Clinical Respiratory …, 2013 - Wiley Online Library
Introduction Hyperglycaemia is a well‐known phenomenon among patients with an
exacerbation of asthma or chronic obstructive pulmonary disease ( COPD ). It may be associated …