Histopathologic changes and SARS-CoV-2 immunostaining in the lung of a patient with COVID-19

H Zhang, P Zhou, Y Wei, H Yue, Y Wang… - Annals of internal …, 2020 - acpjournals.org
Background: Although many studies have demonstrated the epidemiologic characteristics of
SARS-CoV-2 disease (COVID-19), details of pathologic changes in the lung are still lacking…

[HTML][HTML] The laboratory tests and host immunity of COVID-19 patients with different severity of illness

…, W Liu, Y Zhu, Q Lin, L Mao, M Fang, H Zhang… - JCI insight, 2020 - ncbi.nlm.nih.gov
BACKGROUND The coronavirus disease 2019 (COVID-19), infected by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has caused a severe outbreak throughout the …

Clinical characteristics of 54 medical staff with COVID‐19: a retrospective study in a single center in Wuhan, China

…, P Chen, G Li, S Wu, B Zhang, S Zhang… - Journal of medical …, 2020 - Wiley Online Library
In December 2019, an outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS‐Cov‐2)
infection occurred in Wuhan, and rapidly spread to worldwide, which has …

MBD2 serves as a viable target against pulmonary fibrosis by inhibiting macrophage M2 program

…, S Zhang, Q Yu, P Yang, Y Xu, J Zhao, H Zhang… - Science …, 2021 - science.org
Despite past extensive studies, the mechanisms underlying pulmonary fibrosis (PF) still
remain poorly understood. Here, we demonstrated that lungs originating from different types of …

[PDF][PDF] Mesenchymal stem cells transplantation protects against rat pulmonary emphysema

G Zhen, H Liu, N Gu, H Zhang, Y Xu, Z Zhang - Front Biosci, 2008 - article.imrpress.com
Introduction 3. Materials and Methods 3.1. Isolation and expansion of rat bone marrow
MSCs 3.2. Papain-induced pulmonary emphysema and bone marrow MSCs transplantation …

Clinical characteristics of COVID‐19 in patients with preexisting ILD: A retrospective study in a single center in Wuhan, China

H Huang, M Zhang, C Chen, H Zhang… - Journal of medical …, 2020 - Wiley Online Library
Since the outbreak of 2019 novel coronavirus (SARS‐CoV‐2) pneumonia, many patients with
underlying disease, such as interstitial lung disease (ILD), were admitted to Tongji hospital …

Targeting interleukin-13 with tralokinumab attenuates lung fibrosis and epithelial damage in a humanized SCID idiopathic pulmonary fibrosis model

LA Murray, H Zhang, SR Oak, AL Coelho… - American journal of …, 2014 - atsjournals.org
The aberrant fibrotic and repair responses in the lung are major hallmarks of idiopathic
pulmonary fibrosis (IPF). Numerous antifibrotic strategies have been used in the clinic with limited …

IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages

LZ Rao, Y Wang, L Zhang, G Wu, L Zhang… - Cell Death & …, 2021 - nature.com
Idiopathic pulmonary fibrosis (IPF) is the most common type of idiopathic interstitial pneumonia
and has one of the poorest prognosis. However, the molecular mechanisms underlying …

Preparation and characterization of Konjac glucomannan and pullulan composite films for strawberry preservation

Y Yan, S Duan, H Zhang, Y Liu, C Li, B Hu, A Liu… - Carbohydrate …, 2020 - Elsevier
The present study aims to develop the new composite films by blending Konjac glucomannan
(KGM) and pullulan with different ratios and concentrations. The structural, physical, …

Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR

…, AJ Bryer, CM Quinn, G Hou, H Zhang… - Nature structural & …, 2020 - nature.com
HIV-1 capsid plays multiple key roles in viral replication, and inhibition of capsid assembly
is an attractive target for therapeutic intervention. Here, we report the atomic-resolution …