Central sensitization, increased sensitivity in spinal cord dorsal horn neurons after injuries,
plays an essential role in the induction and maintenance of chronic pain. However, synaptic …

Gabapentin, a γ-aminobutyric acid (GABA) analogue anticonvulsant, is also an effective
analgesic agent in neuropathic and inflammatory, but not acute, pain systemically and …

During evolution, living organisms develop a specialized apparatus called nociceptors to
sense their environment and avoid hazardous situations. Intense stimulation of high threshold …

Management of chronic pain, such as nerve-injury-induced neuropathic pain associated with
diabetic neuropathy, viral infection, and cancer, is a real clinical challenge. Major surgeries…

Accurate and rapid identification of pathogenic microorganisms is of critical importance in
disease treatment and public health. Conventional work flows are time-consuming, and …

This study was conducted to investigate the protection of disposable filtering half-facepiece
respirators of different grades against particles between 0.093 and 1.61 𝜇m. A personal …

A-type K + channels (A-channels) are crucial in controlling neuronal excitability, and their
downregulation in pain-sensing neurons may increase pain sensation. To test this hypothesis, …

Nerve injury–induced neuropathic pain is difficult to treat. In this study, we used exosomes
derived from human umbilical cord mesenchymal stem cell (UCMSC) as a cell-free therapy for …

Ovarian cancers are frequently not diagnosed until advanced stages, resulting in a high case
fatality rate. Because of this, more tumor markers, in addition to CA125, for detecting and …

Gentamicin (GM), one of the most commonly used aminoglycoside antibiotics, has been used
for treating pneumonia; however, the applicability of GM is limited by its bioavailability and …