Acellular Normal and Fibrotic Human Lung Matrices as a Culture System for In Vitro Investigation

…, AM Cornett, AA Dreffs, SA Matthes, JL Tsui… - American journal of …, 2012 - atsjournals.org
Rationale: Extracellular matrix (ECM) is a dynamic tissue that contributes to organ integrity
and function, and its regulation of cell phenotype is a major aspect of cell biology. However, …

An essential role for fibronectin extra type III domain A in pulmonary fibrosis

…, KR Flaherty, FJ Martinez, JL Tsui… - American journal of …, 2008 - atsjournals.org
Rationale: Tissue fibrosis is considered a dysregulated wound-healing response. Fibronectin
containing extra type III domain A (EDA) is implicated in the regulation of wound healing. …

Analysis of pulmonary features and treatment approaches in the COPA syndrome

JL Tsui, OA Estrada, Z Deng, KM Wang… - ERJ Open …, 2018 - Eur Respiratory Soc
The COPA syndrome is a monogenic, autoimmune lung and joint disorder first identified in
2015. This study sought to define the main pulmonary features of the COPA syndrome in an …

Control of fibroblast fibronectin expression and alternative splicing via the PI3K/Akt/mTOR pathway

…, M Yan, AM Cornett, CA Bloomheart, JL Tsui… - Experimental cell …, 2010 - Elsevier
Fibronectin (FN), a ubiquitous glycoprotein that plays critical roles in physiologic and pathologic
conditions, undergoes alternative splicing which distinguishes plasma FN (pFN) from …

[HTML][HTML] Phosphatase and tensin homologue on chromosome 10 (PTEN) directs prostaglandin E2-mediated fibroblast responses via regulation of E prostanoid 2 …

RL Sagana, M Yan, AM Cornett, JL Tsui… - Journal of biological …, 2009 - ASBMB
Prostaglandin E 2 (PGE 2 ) is an arachidonic acid metabolite that counters transforming
growth factor-β-induced fibroblast activation via E prostanoid 2 (EP2) receptor binding. …

A 44-Year-Old Man Presenting With Massive Hemoptysis and Dyspnea

…, G Hedstrom, J Levene, S Desai, A Khan, JL Tsui - Chest, 2021 - Elsevier
Case Presentation A 44-year-old man presented to the ED with acute massive hemoptysis
and hypoxia. His history was notable for 1 year of progressively worsening shortness of …

Promoter Methylation Downregulates PTEN Expression In IPF Lung Fibroblasts

…, AJ Booth, AM Cornett, AA Dreffs, JL Tsui… - B64. PATHWAYS …, 2011 - atsjournals.org
Rationale: antagonizes the PI3K/Akt pathway and also inhibits fibroblast activation. We have
shown that activated fibroblasts located within fibroblastic foci in lungs of patients with IPF …

Opioid-free ultra-fast-track on-pump coronary artery bypass grafting using erector spinae plane catheters

…, JL Horn, JH Boyd, BCH Tsui… - … of cardiothoracic and …, 2019 - jcvaonline.com
Modern cardiac anesthesia involves judicious dosing of opioids and hypnotic agents,
facilitating fast-track patient-care pathways with shorter mechanical ventilation times, shorter …

Benefits, Risks, and Challenges of Incisional Analgesia in Pediatric Cardiac Anesthesia

JL Brodt, BCH Tsui - Journal of Cardiothoracic and Vascular …, 2021 - jcvaonline.com
THIS MONTH in the Journal of Cardiothoracic and Vascular Anesthesia, Tirotta et al
presented their experience and analysis using liposomal bupivacaine incisional analgesia in …

The international HapMap project

…, PN Ossorio, VO Wang, CN Rotimi, LC Tsui… - 2003 - deepblue.lib.umich.edu
The goal of the International HapMap Project is to determine the common patterns of DNA
sequence variation in the human genome and to make this information freely available in the …