Clinical Features and Outcome of SARS-CoV-2 Infection in Children: A Systematic Review and Meta-analysis
Objective Knowledge about COVID-19 in children is limited due to the paucity of reported
data. The pediatric age group comprises only less than 5% of total COVID-19 worldwide, …
data. The pediatric age group comprises only less than 5% of total COVID-19 worldwide, …
Energy-stress-mediated AMPK activation inhibits ferroptosis
Energy stress depletes ATP and induces cell death. Here we identify an unexpected
inhibitory role of energy stress on ferroptosis, a form of regulated cell death induced by iron-…
inhibitory role of energy stress on ferroptosis, a form of regulated cell death induced by iron-…
[HTML][HTML] Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
RNA-binding proteins (RBPs) are critical regulators of post-transcriptional gene expression,
and aberrant RBP-RNA interactions can promote cancer progression. Here, we interrogate …
and aberrant RBP-RNA interactions can promote cancer progression. Here, we interrogate …
[HTML][HTML] Salinity stress in potato: Understanding physiological, biochemical and molecular responses
Among abiotic stresses, salinity is a major global threat to agriculture, causing severe damage
to crop production and productivity. Potato (Solanum tuberosum) is regarded as a future …
to crop production and productivity. Potato (Solanum tuberosum) is regarded as a future …
[PDF][PDF] Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer
Many oncogenic insults deregulate RNA splicing, often leading to hypersensitivity of tumors
to spliceosome-targeted therapies (STTs). However, the mechanisms by which STTs …
to spliceosome-targeted therapies (STTs). However, the mechanisms by which STTs …
Clinical features and outcome of SARS-CoV-2 infection in neonates: a systematic review
SK Dhir, J Kumar, J Meena… - Journal of tropical …, 2021 - academic.oup.com
Objective The objective of this study is to systematically synthesize the currently available
literature on various modes of transmission (congenital, intrapartum, and postpartum), clinical …
literature on various modes of transmission (congenital, intrapartum, and postpartum), clinical …
Telomerase abrogates aneuploidy‐induced telomere replication stress, senescence and cell depletion
The causal role of aneuploidy in cancer initiation remains under debate since mutations of
euploidy‐controlling genes reduce cell fitness but aneuploidy strongly associates with human …
euploidy‐controlling genes reduce cell fitness but aneuploidy strongly associates with human …
Mutations in WDR4 as a new cause of Galloway–Mowat syndrome
…, CA Hoogstraten, H Hugo, J Meena… - American journal of …, 2018 - Wiley Online Library
Galloway‐Mowat syndrome (GAMOS) is a phenotypically heterogeneous disorder characterized
by neurodevelopmental defects combined with renal‐glomerular disease, manifesting …
by neurodevelopmental defects combined with renal‐glomerular disease, manifesting …
[HTML][HTML] Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance
How cells coordinate cell cycling with cell survival and death remains incompletely understood.
Here, we show that cell cycle arrest has a potent suppressive effect on ferroptosis, a form …
Here, we show that cell cycle arrest has a potent suppressive effect on ferroptosis, a form …
Incidence of acute kidney injury in hospitalized children: a meta-analysis
METHODS Three different databases were searched (PubMed, Embase, Web of Sciences)
from March 2012 to January 2022 without language or geographical restrictions. We …
from March 2012 to January 2022 without language or geographical restrictions. We …