Accurate phenotyping of patients with pulmonary hypertension (PH) is an integral part of
informing disease classification, treatment, and prognosis. The impact of lung disease on PH …

Background Pulmonary hypertension (PH) in patients with chronic lung disease (CLD) predicts
reduced functional status, clinical worsening and increased mortality, with patients with …

Background: Chronic obstructive pulmonary disease (COPD) is a known comorbidity for lung
cancer independent of smoking history. Quantitative computed tomography (qCT) imaging …

Feature selection is an important aspect of computer-aided classification system design. We
have developed an in-house computer-aided diagnosis (CAD) tool for computed …

Neurofibromatosis type 1 (NF1) is a rare, autosomal dominant disease with variable clinical
presentations. Large animal models are useful to help dissect molecular mechanisms, …

Medical imaging is a powerful tool for clinical practice allowing in-vivo insight into a patient’s
disease state. Many modalities exist, allowing for the collection of diverse information about …

Rationale: Chronic obstructive pulmonary disease (COPD) is a known risk factor for lung
cancer irrespective of smoking history. Previous studies have linked whole-lung imaging …

To determine the optimal number of clusters, k, an iterative testing procedure is performed
for all valid k-values (k=[2,# features (304)]), optimizing over the average cluster silhouette …

Purpose Computed tomography (CT) is an effective method for detecting and characterizing
lung nodules in vivo. With the growing use of chest CT, the detection frequency of lung …

Objectives Post-imaging mathematical prediction models (MPMs) provide guidance for the
management of solid pulmonary nodules by providing a lung cancer risk score from …