User profiles for John C. Waterton

John Waterton

University of Manchester
Verified email at manchester.ac.uk
Cited by 13958

Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field

KR Thulborn, JC Waterton, PM Matthews… - Biochimica et Biophysica …, 1982 - Elsevier
At high and medium magnetic field, the transverse NMR relaxation rate (T 2 −1 ) of water
protons in blood is determined predominantly by the oxygenation state of haemoglobin. T 2 −1 …

[HTML][HTML] Imaging biomarker roadmap for cancer studies

…, LM McShane, A Jackson, JC Waterton - Nature reviews Clinical …, 2017 - nature.com
Imaging biomarkers (IBs) are integral to the routine management of patients with cancer. IBs
used daily in oncology include clinical TNM stage, objective response and left ventricular …

A minimum description length approach to statistical shape modeling

…, CJ Twining, TF Cootes, JC Waterton… - IEEE transactions on …, 2002 - ieeexplore.ieee.org
We describe a method for automatically building statistical shape models from a training set
of example boundaries/surfaces. These models show considerable promise as a basis for …

[HTML][HTML] The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations

…, PS Tofts, GM Tozer, W Vennart, JC Waterton… - British journal of …, 2005 - nature.com
Vascular and angiogenic processes provide an important target for novel cancer therapeutics.
Dynamic contrast-enhanced magnetic resonance imaging is being used increasingly to …

Imaging intratumor heterogeneity: role in therapy response, resistance, and clinical outcome

JPB O'Connor, CJ Rose, JC Waterton… - Clinical Cancer …, 2015 - AACR
Tumors exhibit genomic and phenotypic heterogeneity, which has prognostic significance
and may influence response to therapy. Imaging can quantify the spatial variation in …

[HTML][HTML] Magnetic resonance imaging (MRI) of articular cartilage in knee osteoarthritis (OA): morphological assessment

…, F Cicuttini, JP Raynauld, JC Waterton, C Peterfy - Osteoarthritis and …, 2006 - Elsevier
OBJECTIVE: Magnetic resonance imaging (MRI) is a three-dimensional imaging technique
with unparalleled ability to evaluate articular cartilage. This report reviews the current status …

Effect of rosuvastatin therapy on carotid plaque morphology and composition in moderately hypercholesterolemic patients: a high-resolution magnetic resonance …

…, B Neradilek, JS Raichlen, VA Cain, JC Waterton… - American heart …, 2008 - Elsevier
BACKGROUND: Magnetic resonance imaging (MRI) can noninvasively assess changes in
atherosclerotic plaque morphology and composition. The ORION trial assessed the effects of …

[HTML][HTML] Drug-induced interstitial lung disease: a systematic review

…, C Hayton, A Giollo, JM Wild, JC Waterton… - Journal of clinical …, 2018 - mdpi.com
Background: Drug-induced interstitial lung disease (DIILD) occurs as a result of numerous
agents, but the risk often only becomes apparent after the marketing authorisation of such …

3D statistical shape models using direct optimisation of description length

RH Davies, CJ Twining, TF Cootes, JC Waterton… - … Vision—ECCV 2002 …, 2002 - Springer
We describe an automatic method for building optimal 3D statistical shape models from sets
of training shapes. Although shape models show considerable promise as a basis for …

Oxygen-enhanced MRI accurately identifies, quantifies, and maps tumor hypoxia in preclinical cancer models

…, A Jackson, GJM Parker, AR Reynolds, JC Waterton… - Cancer research, 2016 - AACR
There is a clinical need for noninvasive biomarkers of tumor hypoxia for prognostic and
predictive studies, radiotherapy planning, and therapy monitoring. Oxygen-enhanced MRI (OE-…