User profiles for John C. Waterton
John WatertonUniversity of Manchester Verified email at manchester.ac.uk Cited by 13958 |
Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field
KR Thulborn, JC Waterton, PM Matthews… - Biochimica et Biophysica …, 1982 - Elsevier
At high and medium magnetic field, the transverse NMR relaxation rate (T 2 −1 ) of water
protons in blood is determined predominantly by the oxygenation state of haemoglobin. T 2 −1 …
protons in blood is determined predominantly by the oxygenation state of haemoglobin. T 2 −1 …
[HTML][HTML] Imaging biomarker roadmap for cancer studies
Imaging biomarkers (IBs) are integral to the routine management of patients with cancer. IBs
used daily in oncology include clinical TNM stage, objective response and left ventricular …
used daily in oncology include clinical TNM stage, objective response and left ventricular …
A minimum description length approach to statistical shape modeling
We describe a method for automatically building statistical shape models from a training set
of example boundaries/surfaces. These models show considerable promise as a basis for …
of example boundaries/surfaces. These models show considerable promise as a basis for …
[HTML][HTML] The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations
…, PS Tofts, GM Tozer, W Vennart, JC Waterton… - British journal of …, 2005 - nature.com
Vascular and angiogenic processes provide an important target for novel cancer therapeutics.
Dynamic contrast-enhanced magnetic resonance imaging is being used increasingly to …
Dynamic contrast-enhanced magnetic resonance imaging is being used increasingly to …
Imaging intratumor heterogeneity: role in therapy response, resistance, and clinical outcome
JPB O'Connor, CJ Rose, JC Waterton… - Clinical Cancer …, 2015 - AACR
Tumors exhibit genomic and phenotypic heterogeneity, which has prognostic significance
and may influence response to therapy. Imaging can quantify the spatial variation in …
and may influence response to therapy. Imaging can quantify the spatial variation in …
[HTML][HTML] Magnetic resonance imaging (MRI) of articular cartilage in knee osteoarthritis (OA): morphological assessment
…, F Cicuttini, JP Raynauld, JC Waterton, C Peterfy - Osteoarthritis and …, 2006 - Elsevier
OBJECTIVE: Magnetic resonance imaging (MRI) is a three-dimensional imaging technique
with unparalleled ability to evaluate articular cartilage. This report reviews the current status …
with unparalleled ability to evaluate articular cartilage. This report reviews the current status …
Effect of rosuvastatin therapy on carotid plaque morphology and composition in moderately hypercholesterolemic patients: a high-resolution magnetic resonance …
…, B Neradilek, JS Raichlen, VA Cain, JC Waterton… - American heart …, 2008 - Elsevier
BACKGROUND: Magnetic resonance imaging (MRI) can noninvasively assess changes in
atherosclerotic plaque morphology and composition. The ORION trial assessed the effects of …
atherosclerotic plaque morphology and composition. The ORION trial assessed the effects of …
[HTML][HTML] Drug-induced interstitial lung disease: a systematic review
Background: Drug-induced interstitial lung disease (DIILD) occurs as a result of numerous
agents, but the risk often only becomes apparent after the marketing authorisation of such …
agents, but the risk often only becomes apparent after the marketing authorisation of such …
3D statistical shape models using direct optimisation of description length
We describe an automatic method for building optimal 3D statistical shape models from sets
of training shapes. Although shape models show considerable promise as a basis for …
of training shapes. Although shape models show considerable promise as a basis for …
Oxygen-enhanced MRI accurately identifies, quantifies, and maps tumor hypoxia in preclinical cancer models
There is a clinical need for noninvasive biomarkers of tumor hypoxia for prognostic and
predictive studies, radiotherapy planning, and therapy monitoring. Oxygen-enhanced MRI (OE-…
predictive studies, radiotherapy planning, and therapy monitoring. Oxygen-enhanced MRI (OE-…