Eosinophil-guided corticosteroid therapy in patients admitted to hospital with COPD exacerbation (CORTICO-COP): a multicentre, randomised, controlled, open-label …
…, RR Laub, M Moberg, CS Bech, J Eklöf… - The Lancet …, 2019 - thelancet.com
Background Treatment with systemic corticosteroids in patients with acute exacerbations of
chronic obstructive pulmonary disease (COPD) is associated with debilitating adverse effects…
chronic obstructive pulmonary disease (COPD) is associated with debilitating adverse effects…
[HTML][HTML] Azithromycin and hydroxychloroquine in hospitalised patients with confirmed COVID-19: a randomised double-blinded placebo-controlled trial
…, TS Lapperre, RD Bojesen, J Eklöf… - European …, 2022 - Eur Respiratory Soc
Background Combining the antibiotic azithromycin and hydroxychloroquine induces airway
immunomodulatory effects, with the latter also having in vitro antiviral properties. This may …
immunomodulatory effects, with the latter also having in vitro antiviral properties. This may …
Use of inhaled corticosteroids and risk of acquiring Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease
J Eklöf, TS Ingebrigtsen, R Sørensen, MI Saeed… - Thorax, 2022 - thorax.bmj.com
Background Inhaled corticosteroids (ICS) are commonly used to treat COPD and are associated
with increased risk of pneumonia. The aim of this study was to assess if accumulated …
with increased risk of pneumonia. The aim of this study was to assess if accumulated …
[HTML][HTML] Antibiotic treatment adequacy and death among patients with Pseudomonas aeruginosa airway infection
J Eklöf, KM Gliese, TS Ingebrigtsen, U Bodtger… - PLoS …, 2019 - journals.plos.org
Objective The effect of antibiotics on survival in patients with pulmonary Pseudomonas
aeruginosa is controversial. The aim of this study is to i) determine the prevalence of adequate …
aeruginosa is controversial. The aim of this study is to i) determine the prevalence of adequate …
COPD exacerbations: the impact of long versus short courses of oral corticosteroids on mortality and pneumonia: nationwide data on 67 000 patients with COPD …
…, CB Jensen, KH Allin, J Eklöf… - BMJ open …, 2019 - bmjopenrespres.bmj.com
Introduction A large group of patients with chronic obstructive pulmonary disease (COPD)
are exposed to an overload of oral corticosteroids (OCS) due to repeated exacerbations. This …
are exposed to an overload of oral corticosteroids (OCS) due to repeated exacerbations. This …
[HTML][HTML] Hospitalization for chronic obstructive pulmonary disease and pneumonia: association with the dose of inhaled corticosteroids. A nation-wide cohort study of …
C Rønn, P Sivapalan, J Eklöf, P Kamstrup… - Clinical Microbiology …, 2023 - Elsevier
Objectives International guidelines only advocate the use of inhaled corticosteroids (ICSs)
in patients with chronic obstructive pulmonary disease (COPD) experiencing recurring …
in patients with chronic obstructive pulmonary disease (COPD) experiencing recurring …
Use of inhaled corticosteroids and the risk of developing type 2 diabetes in patients with chronic obstructive pulmonary disease
MI Saeed, J Eklöf, I Achir, P Sivapalan… - Diabetes, Obesity …, 2020 - Wiley Online Library
Aim To determine the risk of type 2 diabetes onset associated with accumulated inhaled
corticosteroids (ICS) dose during the previous year in patients with chronic obstructive …
corticosteroids (ICS) dose during the previous year in patients with chronic obstructive …
Inhaled corticosteroids and risk of lower respiratory tract infection with Moraxella catarrhalis in patients with chronic obstructive pulmonary disease
…, C Ostergaard, P Sivapalan, J Eklöf… - BMJ open …, 2023 - bmjopenrespres.bmj.com
Background Use of inhaled corticosteroids (ICS) is common in patients with chronic
obstructive pulmonary disease (COPD) and has been associated with an increased risk of …
obstructive pulmonary disease (COPD) and has been associated with an increased risk of …
[HTML][HTML] Persistence and genetic adaptation of Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease
J Eklöf, MA Misiakou, P Sivapalan, K Armbruster… - Clinical Microbiology …, 2022 - Elsevier
Objectives It is unclear whether recurrent sputum culture with Pseudomonas aeruginosa
from patients with chronic obstructive pulmonary disease (COPD) is caused by intermittent …
from patients with chronic obstructive pulmonary disease (COPD) is caused by intermittent …
[HTML][HTML] Use of Inhaled Corticosteroids and Risk of Acquiring Haemophilus influenzae in Patients with Chronic Obstructive Pulmonary Disease
RU Mohsin, CK Heerfordt, J Eklöf, P Sivapalan… - Journal of Clinical …, 2022 - mdpi.com
Background: Inhaled corticosteroids (ICS) are widely used in chronic obstructive pulmonary
disease (COPD), despite the known risk of severe adverse effects including pulmonary …
disease (COPD), despite the known risk of severe adverse effects including pulmonary …