Eosinophil-guided corticosteroid therapy in patients admitted to hospital with COPD exacerbation (CORTICO-COP): a multicentre, randomised, controlled, open-label …

…, RR Laub, M Moberg, CS Bech, J Eklöf… - The Lancet …, 2019 - thelancet.com
Background Treatment with systemic corticosteroids in patients with acute exacerbations of
chronic obstructive pulmonary disease (COPD) is associated with debilitating adverse effects…

[HTML][HTML] Azithromycin and hydroxychloroquine in hospitalised patients with confirmed COVID-19: a randomised double-blinded placebo-controlled trial

…, TS Lapperre, RD Bojesen, J Eklöf… - European …, 2022 - Eur Respiratory Soc
Background Combining the antibiotic azithromycin and hydroxychloroquine induces airway
immunomodulatory effects, with the latter also having in vitro antiviral properties. This may …

Use of inhaled corticosteroids and risk of acquiring Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease

J Eklöf, TS Ingebrigtsen, R Sørensen, MI Saeed… - Thorax, 2022 - thorax.bmj.com
Background Inhaled corticosteroids (ICS) are commonly used to treat COPD and are associated
with increased risk of pneumonia. The aim of this study was to assess if accumulated …

[HTML][HTML] Antibiotic treatment adequacy and death among patients with Pseudomonas aeruginosa airway infection

J Eklöf, KM Gliese, TS Ingebrigtsen, U Bodtger… - PLoS …, 2019 - journals.plos.org
Objective The effect of antibiotics on survival in patients with pulmonary Pseudomonas
aeruginosa is controversial. The aim of this study is to i) determine the prevalence of adequate …

COPD exacerbations: the impact of long versus short courses of oral corticosteroids on mortality and pneumonia: nationwide data on 67 000 patients with COPD …

…, CB Jensen, KH Allin, J Eklöf… - BMJ open …, 2019 - bmjopenrespres.bmj.com
Introduction A large group of patients with chronic obstructive pulmonary disease (COPD)
are exposed to an overload of oral corticosteroids (OCS) due to repeated exacerbations. This …

[HTML][HTML] Hospitalization for chronic obstructive pulmonary disease and pneumonia: association with the dose of inhaled corticosteroids. A nation-wide cohort study of …

C Rønn, P Sivapalan, J Eklöf, P Kamstrup… - Clinical Microbiology …, 2023 - Elsevier
Objectives International guidelines only advocate the use of inhaled corticosteroids (ICSs)
in patients with chronic obstructive pulmonary disease (COPD) experiencing recurring …

Use of inhaled corticosteroids and the risk of developing type 2 diabetes in patients with chronic obstructive pulmonary disease

MI Saeed, J Eklöf, I Achir, P Sivapalan… - Diabetes, Obesity …, 2020 - Wiley Online Library
Aim To determine the risk of type 2 diabetes onset associated with accumulated inhaled
corticosteroids (ICS) dose during the previous year in patients with chronic obstructive …

Inhaled corticosteroids and risk of lower respiratory tract infection with Moraxella catarrhalis in patients with chronic obstructive pulmonary disease

…, C Ostergaard, P Sivapalan, J Eklöf… - BMJ open …, 2023 - bmjopenrespres.bmj.com
Background Use of inhaled corticosteroids (ICS) is common in patients with chronic
obstructive pulmonary disease (COPD) and has been associated with an increased risk of …

[HTML][HTML] Persistence and genetic adaptation of Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease

J Eklöf, MA Misiakou, P Sivapalan, K Armbruster… - Clinical Microbiology …, 2022 - Elsevier
Objectives It is unclear whether recurrent sputum culture with Pseudomonas aeruginosa
from patients with chronic obstructive pulmonary disease (COPD) is caused by intermittent …

[HTML][HTML] Use of Inhaled Corticosteroids and Risk of Acquiring Haemophilus influenzae in Patients with Chronic Obstructive Pulmonary Disease

RU Mohsin, CK Heerfordt, J Eklöf, P Sivapalan… - Journal of Clinical …, 2022 - mdpi.com
Background: Inhaled corticosteroids (ICS) are widely used in chronic obstructive pulmonary
disease (COPD), despite the known risk of severe adverse effects including pulmonary …