Rationale: In pulmonary arterial hypertension (PAH), endothelial dysfunction and obliterative
vascular disease are associated with DNA damage and impaired signaling of BMPR2 (…

The serine protease inhibitor neuroserpin regulates the activity of tissue-type plasminogen
activator (tPA) in the nervous system. Neuroserpin expression is particularly prominent at late …

Dysfunction of the pulmonary endothelium is associated with most lung diseases. Extracellular
nucleotides modulate a plethora of endothelial functions in the lung such as vessel …

Adeno-associated viral (AAV) vectors are becoming increasingly popular in basic research
as well as in clinical gene therapy. Due to its exceptional resistance against physical and …

Background Converging evidence from proteogenomic analyses prioritises thrombospondin-2
(TSP2) as a potential biomarker for idiopathic or heritable pulmonary arterial …

Epilepsy is one of the most common neurological diseases worldwide with about 50 million
people suffering from this disease according to the World Health Organization. In infancy, …

Digital transformation activities have been carried out in the field of calibration since 2017,
in particularly with the digital calibration certificates (DCCs). From the very beginning, these …

During ion exchange under atmospheric conditions, zeolites A, X, and Y facilitate the oxidation
of Fe 2+ to Fe 3+ to very different extents, ranging from complete oxidation of the ferrous …

… We greatly acknowledge expert technical assistance by Julia Mienert, MSc. … Hennigs
JK, Cao A, Li CG, Shi M, Mienert J, Miyagawa K, et al. PPARgamma-p53-mediated …

Warming of the Arctic led to an increase in permafrost temperatures by about 0.3 ∘ C during
the last decade. Permafrost warming is associated with increasing sediment water content, …