[HTML][HTML] Non-canonical kinase signaling by the death ligand TRAIL in cancer cells: discord in the death receptor family
K Azijli, B Weyhenmeyer, GJ Peters… - Cell Death & …, 2013 - nature.com
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-based therapy is currently
evaluated in clinical studies as a tumor cell selective pro-apoptotic approach. However, …
evaluated in clinical studies as a tumor cell selective pro-apoptotic approach. However, …
New developments in the treatment of metastatic melanoma: immune checkpoint inhibitors and targeted therapies
K Azijli, E Stelloo, GJ Peters… - Anticancer …, 2014 - ar.iiarjournals.org
The incidence of melanoma has been increasing over the past twenty years. Unfortunately,
the prognosis of advanced-stage disease is still poor. Advances have been made in the …
the prognosis of advanced-stage disease is still poor. Advances have been made in the …
[HTML][HTML] Chest CT in COVID-19 at the ED: validation of the COVID-19 reporting and data system (CO-RADS) and CT severity score: a prospective, multicenter …
AWE Lieveld, K Azijli, BP Teunissen, RM van Haaften… - Chest, 2021 - Elsevier
Background CT is thought to play a key role in coronavirus disease 2019 (COVID-19)
diagnostic workup. The possibility of comparing data across different settings depends on the …
diagnostic workup. The possibility of comparing data across different settings depends on the …
[HTML][HTML] Diagnosing COVID-19 pneumonia in a pandemic setting: Lung Ultrasound versus CT (LUVCT)–a multicentre, prospective, observational study
AWE Lieveld, B Kok, FH Schuit, K Azijli… - ERJ Open …, 2020 - Eur Respiratory Soc
Background In this coronavirus disease 2019 (COVID-19) pandemic, fast and accurate
testing is needed to profile patients at the emergency department (ED) and efficiently allocate …
testing is needed to profile patients at the emergency department (ED) and efficiently allocate …
Kinome profiling of non-canonical TRAIL signaling reveals RIP1–Src–STAT3-dependent invasion in resistant non-small cell lung cancer cells
K Azijli, S Yuvaraj, MP Peppelenbosch… - Journal of cell …, 2012 - journals.biologists.com
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) triggers apoptosis
selectively in tumor cells through interaction with TRAIL-R1/DR4 or TRAIL-R2/DR5 and this …
selectively in tumor cells through interaction with TRAIL-R1/DR4 or TRAIL-R2/DR5 and this …
[HTML][HTML] Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib
…, RJ Honeywell, H Dekker, D Poel, K Azijli… - Cellular oncology, 2015 - Springer
Purpose When during cancer treatment resistance to a tyrosine kinase inhibitor (TKI) occurs,
switching to another TKI is often considered as a reasonable option. Previously, we …
switching to another TKI is often considered as a reasonable option. Previously, we …
[HTML][HTML] The potential role of lysosomal sequestration in sunitinib resistance of renal cell cancer
K Azijli, KJ Gotink, HMW Verheul - Journal of Kidney Cancer and …, 2015 - ncbi.nlm.nih.gov
Renal cell carcinoma (RCC) is a highly vascularized tumor type, which is often associated
with inactivated mutations in the von Hippel-Lindau gene that drives proangiogenic signaling …
with inactivated mutations in the von Hippel-Lindau gene that drives proangiogenic signaling …
Assessing COVID‐19 pneumonia—clinical extension and risk with point‐of‐care ultrasound: a multicenter, prospective, observational study
AWE Lieveld, B Kok, K Azijli, FH Schuit… - Journal of the …, 2021 - Wiley Online Library
Background Assessing the extent of lung involvement is important for the triage and care of
COVID‐19 pneumonia. We sought to determine the utility of point‐of‐care ultrasound (…
COVID‐19 pneumonia. We sought to determine the utility of point‐of‐care ultrasound (…
MAPK p38 and JNK have opposing activities on TRAIL-induced apoptosis activation in NSCLC H460 cells that involves RIP1 and caspase-8 and is mediated by Mcl-1
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can induce both caspase-dependent
apoptosis and kinase activation in tumor cells. Here, we examined the …
apoptosis and kinase activation in tumor cells. Here, we examined the …
[HTML][HTML] Routine screening for pulmonary embolism in COVID-19 patients at the emergency department: impact of D-dimer testing followed by CTPA
DA Korevaar, I Aydemir, MW Minnema, K Azijli… - Journal of Thrombosis …, 2021 - Springer
COVID-19 patients have increased risk of pulmonary embolism (PE), but symptoms of both
conditions overlap. Because screening algorithms for PE in COVID-19 patients are currently …
conditions overlap. Because screening algorithms for PE in COVID-19 patients are currently …