User profiles for Katie L. Horton

Katie Leanne Horton

Researcher, University of Southampton
Verified email at soton.ac.uk
Cited by 1709

[HTML][HTML] A revised protocol for culture of airway epithelial cells as a diagnostic tool for primary ciliary dyskinesia

JL Coles, J Thompson, KL Horton, RA Hirst… - Journal of Clinical …, 2020 - mdpi.com
Air–liquid interface (ALI) culture of nasal epithelial cells is a valuable tool in the diagnosis
and research of primary ciliary dyskinesia (PCD). Ex vivo samples often display secondary …

The BEAT-PCD (better experimental approaches to treat primary ciliary dyskinesia) clinical research collaboration

…, E Dehlink, R Gaupmann, KL Horton… - European …, 2021 - Eur Respiratory Soc
The need for collaborative research networks as an effective way forward to improve
diagnosis and care of rare inherited diseases is constantly highlighted and primary ciliary …

[HTML][HTML] Epithelial immune activation and intracellular invasion by non-typeable Haemophilus influenzae

…, SB Morgan, GE Donachie, KL Horton… - Frontiers in Cellular …, 2023 - frontiersin.org
Type-2 low asthma affects 30-50% of people with severe asthma and includes a phenotype
characterised by sputum neutrophilia and resistance to corticosteroids. Airways inflammation …

[HTML][HTML] Temporal Whole-Transcriptomic Analysis of Characterized In Vitro and Ex Vivo Primary Nasal Epithelia

J Legebeke, KL Horton, CL Jackson, J Coles… - Frontiers in Cell and …, 2022 - frontiersin.org
Air-liquid interface (ALI) cell culture of primary airway progenitors enables the differentiation
and recapitulation of a pseudostratified epithelium in vitro, providing a highly useful tool for …

[HTML][HTML] Proceedings of the 4th BEAT-PCD Conference and 5th PCD Training School

LE Gardner, KL Horton, A Shoemark, JS Lucas… - BMC proceedings, 2020 - Springer
Primary ciliary dyskinesia (PCD) is an inherited ciliopathy leading to chronic suppurative lung
disease, chronic rhinosinusitis, middle ear disease, sub-fertility and situs abnormalities. As …

ERS International congress 2022: highlights from the respiratory infections assembly

…, K Chichirelo-Konstantynovych, KL Horton… - ERJ Open …, 2023 - Eur Respiratory Soc
The European Respiratory Society International Congress took place both in person, in
Barcelona, Spain, and online in 2022. The congress welcomed over 19 000 attendees on this …

ERS International Congress 2021: highlights from the Respiratory Infections Assembly

…, KD Chichirelo-Konstantynovych, KL Horton… - ERJ Open …, 2022 - Eur Respiratory Soc
The European Respiratory Society International Congress 2021 took place virtually for the
second year running due to the coronavirus pandemic. The Congress programme featured …

Proteomic profiling of air-liquid-interface (ALI)-cultured primary ciliary dyskinesia (PCD) nasal epithelia

KL Horton, JL Coles, CL Jackson, A Bailey, PJ Skipp… - 2023 - Eur Respiratory Soc
PCD is a motile ciliopathy associated with persistent airways infections, chronic inflammation
and bronchiectasis. Besides a characteristic lack of mucociliary clearance, other intrinsic …

[PDF][PDF] Conference and 5 th PCD Training School

LE Gardner, KL Horton, A Shoemark, JS Lucas… - 2020 - bmcproc.biomedcentral.com
Primary ciliary dyskinesia (PCD) is an inherited ciliopathy leading to chronic suppurative lung
disease, chronic rhinosinusitis, middle ear disease, sub-fertility and situs abnormalities. As …

Non-typeable Haemophilus influenzae biofilm formation on primary human airway epithelia cultured at air-liquid interface

KL Horton, JL Coles, JF Hueppe, DW Cleary… - 2022 - microbiologyresearch.org
Introduction Primary ciliary dyskinesia (PCD) is an inherited heterogeneous disorder associated
with defective motile cilia on airway epithelia, resulting in impaired mucociliary function …