User profiles for Kenneth N. Olivier

Kenneth N Olivier

Clinical Professor of Medicine, University of North Carolina at Chapel Hill
Verified email at med.unc.edu
Cited by 30387

[PDF][PDF] SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract

…, RE Lee, BL Yount, TM Mascenik, G Chen, KN Olivier… - Cell, 2020 - cell.com
The mode of acquisition and causes for the variable clinical spectrum of coronavirus disease
2019 (COVID-19) remain unknown. We utilized a reverse genetics system to generate a …

Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline

…, P Leitman, TK Marras, KN Olivier… - Clinical Infectious …, 2020 - academic.oup.com
Nontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of
which can produce disease in humans of all ages and can affect both pulmonary and …

Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

…, D Kleiner, LD Notarangelo, Y Rampertaap, KN Olivier… - Science, 2014 - science.org
Cytotoxic T lymphocyte antigen–4 (CTLA-4) is an inhibitory receptor found on immune cells.
The consequences of mutations in CTLA4 in humans are unknown. We identified germline …

Dominant-activating germline mutations in the gene encoding the PI (3) K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

…, A Agharahimi, AA Hussey, LR Folio, KN Olivier… - Nature …, 2014 - nature.com
The p110δ subunit of phosphatidylinositol-3-OH kinase (PI(3)K) is selectively expressed in
leukocytes and is critical for lymphocyte biology. Here we report fourteen patients from seven …

Nontuberculous mycobacteria: I: multicenter prevalence study in cystic fibrosis

KN Olivier, DJ Weber, RJ Wallace Jr… - American journal of …, 2003 - atsjournals.org
… Correspondence and requests for reprints should be addressed to Kenneth N. Olivier, MD,
MPH, Wilford Hall USAF Medical Center, 759 MSGS/MCCP (Pulmonary/Critical Care), 2200 …

GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity

…, EW Cowen, AF Freeman, KN Olivier… - Blood, The Journal …, 2014 - ashpublications.org
Haploinsufficiency of the hematopoietic transcription factor GATA2 underlies monocytopenia
and mycobacterial infections; dendritic cell, monocyte, B, and natural killer (NK) lymphoid …

[HTML][HTML] Linezolid for treatment of chronic extensively drug-resistant tuberculosis

…, I Jeong, JS Joh, RY Chen, KN Olivier… - … England Journal of …, 2012 - Mass Medical Soc
Background Linezolid has antimycobacterial activity in vitro and is increasingly used for
patients with highly drug-resistant tuberculosis. Methods We enrolled 41 patients who had …

Prevalence of nontuberculous mycobacterial lung disease in US Medicare beneficiaries

J Adjemian, KN Olivier, AE Seitz… - American journal of …, 2012 - atsjournals.org
Rationale: Pulmonary nontuberculous mycobacteria (PNTM) are an important cause of morbidity
among older adults in the United States, but national prevalence estimates are lacking. …

Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome

…, RD Auth, AF Freeman, KN Olivier… - Blood, The Journal …, 2011 - ashpublications.org
The syndrome of monocytopenia, B-cell and NK-cell lymphopenia, and mycobacterial,
fungal, and viral infections is associated with myelodysplasia, cytogenetic abnormalities, …

Nontuberculous mycobacterial lung disease prevalence at four integrated health care delivery systems

…, YR Shea, AE Seitz, SM Holland, KN Olivier - American journal of …, 2010 - atsjournals.org
Rationale: Single-site clinic-based studies suggest an increasing prevalence of pulmonary
nontuberculous mycobacteria (NTM) disease, but systematic data are lacking. Objectives: To …