Fibrosis is an incurable disorder of unknown etiology. Segregated-nucleus-containing
atypical monocytes (SatMs) are critical for the development of fibrosis. Here we examined the …

Monocytes and macrophages comprise a variety of subsets with diverse functions 1 , 2 , 3 , 4
, 5 . It is thought that these cells play a crucial role in homeostasis of peripheral organs, key …

The development of effective treatments against cancers is urgently needed, and the
accumulation of CD8 + T cells within tumors is especially important for cancer prognosis. Although …

The aim of this study was to investigate the clinical impact of sarcopenia on the efficacy of
programmed death (PD)-1 inhibitors. We retrospectively reviewed the medical records of all …

Immune checkpoint inhibitors (ICIs) have caused revolutionary changes in cancer treatment,
but low response rates remain a challenge. Semaphorin 4A (Sema4A) modulates the …

Background The impact of SARS-CoV-2 infection on the gut fungal (mycobiota) and bacterial
(microbiota) communities has been elucidated individually. This study analyzed both gut …

The incidence and prevalence of non-tuberculous mycobacteria (NTM) infections are steadily
increasing worldwide, partially due to the increased incidence of immunocompromised …

Coronavirus disease 2019 (COVID‐19) can cause severe lymphopenia and respiratory failure
requiring prolonged invasive mechanical ventilation (MV). COVID‐19 patients with severe …

Anti-programmed cell death-1 (PD-1) therapy exerts beneficial effects in a limited population
of cancer patients. Therefore, more accurate diagnostics to predict the efficacy of anti-PD-1 …

The combination of rifamycin (RFP), ethambutol (EB), and macrolides is currently the
standard regimen for treatment of Mycobacterium avium complex pulmonary disease (MAC-PD). …