Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts

…, V Ntafis, I Vamvakaris, E Kaniaris, K Vachlas… - Journal of Experimental …, 2022 - rupress.org
A key unknown of the functional space in tumor immunity is whether CD4 T cells depend on
intratumoral MHCII cancer antigen recognition. MHCII-expressing, antigen-presenting cancer…

Multicenter international randomized comparison of objective and subjective outcomes between electronic and traditional chest drainage systems

…, K Papagiannopoulos, A Sihoe, K Vachlas… - The Annals of Thoracic …, 2014 - Elsevier
Background The aim of this study was to assess the impact of digital versus traditional
drainage devices on chest tube removal and patient satisfaction. Methods A randomized trial of …

[HTML][HTML] COVID-19 patients presenting with post-intubation upper airway complications: a parallel epidemic?

…, K Bakiri, P Emmanouil, C Zisis, K Vachlas… - Journal of Clinical …, 2022 - mdpi.com
During the current pandemic, we witnessed a rise of post-intubation tracheal stenosis (PITS)
in patients intubated due to COVID-19. We prospectively analyzed data from patients …

Thymoma and myasthenia gravis: clinical aspects and prognosis

K Vachlas, C Zisis, D Rontogianni… - Asian …, 2012 - journals.sagepub.com
Myasthenia gravis is present in a significant proportion of patients with thymoma. We
investigated particular features of the clinical behavior of thymoma and its relationship to …

[HTML][HTML] Generation of non-small cell lung cancer patient-derived xenografts to study intratumor heterogeneity

…, EI Athanasiadis, I Vamvakaris, E Patsea, K Vachlas… - Cancers, 2021 - mdpi.com
Simple Summary It is widely thought that tumors are composed of different subpopulations
of cancer cells carrying genetic alterations with some of them being common among all cells …

[HTML][HTML] Castleman's disease-a diagnostic dilemma

A Barua, K Vachlas, R Milton, JAC Thorpe - Journal of Cardiothoracic …, 2014 - Springer
Castleman’s disease is a benign lymphoproliferative disease characterised by hyperplasia of
lymphoid follicles. It can affect any lymph nodes in the body. Here we describe a caucasian …

Antigen-presenting fibroblasts sustain anti-tumour CD4+ T cells in situ via MHCIIp-TCR and C1q-C1qbp binding

…, A Prados, G Vamvakaris, E Kaniaris, K Vachlas… - bioRxiv, 2020 - biorxiv.org
In situ antigen presentation is required to sustain active proliferating CD4 + T cells in
tumours and to help form memory CD8 + T cells, but the antigen presenting cells (APCs) and …

Tumor MHCII immunity requires in situ antigen presentation by cancer-associated fibroblasts.

…, C Tzaferis, I Vamvakaris, E Kaniaris, K Vachlas… - 2021 - researchsquare.com
A key unknown of the functional space in tumor immunity is whether physiologically relevant
cancer antigen presentation occurs solely in draining lymph nodes versus tumors. …

Recurrence in patients that underwent surgery for lung cancer.

E Sepsas, K Vachlas, S Gaitanakis, L Toufektzian… - …, 2017 - search.ebscohost.com
Intro duction: The recording and analysis of lung cancer recurrences in patients with primary
non-small cell lung cancer that initially underwent radical surgical treatment. Metho d: This …

A 63-Year-Old Woman With Pulmonary Micronodules and Chronic Cough

V Tzilas, P Kyriazis, A Tzouvelekis, K Vachlas… - Chest, 2019 - Elsevier
Case Presentation A 63-year-old woman presented with a 2-year history of nonproductive
cough. She denied the presence of shortness of breath, chest pain, arthralgia, muscle …