Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke …
Background and Purpose— This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …
Cerebral microbleeds: a guide to detection and interpretation
…, RAS Salman, S Warach, LJ Launer… - The Lancet …, 2009 - thelancet.com
Cerebral microbleeds (CMBs) are increasingly recognised neuroimaging findings in
individuals with cerebrovascular disease and dementia, and in normal ageing. There has been …
individuals with cerebrovascular disease and dementia, and in normal ageing. There has been …
Impact of hypertension on cognitive function: a scientific statement from the American Heart Association
…, M Gulati, H Kamel, DS Knopman, LJ Launer… - …, 2016 - Am Heart Assoc
Background— Age-related dementia, most commonly caused by Alzheimer disease or
cerebrovascular factors (vascular dementia), is a major public health threat. Chronic arterial …
cerebrovascular factors (vascular dementia), is a major public health threat. Chronic arterial …
Biological, clinical and population relevance of 95 loci for blood lipids
…, ML Lokki, G Lettre, C Langenberg, LJ Launer… - Nature, 2010 - nature.com
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density
lipoprotein cholesterol and triglycerides are among the most important risk factors for …
lipoprotein cholesterol and triglycerides are among the most important risk factors for …
Genome-wide association study identifies 74 loci associated with educational attainment
Educational attainment is strongly influenced by social and other environmental factors, but
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …
Intensive vs standard blood pressure control and cardiovascular disease outcomes in adults aged≥ 75 years: a randomized clinical trial
…, DW Kitzman, JB Kostis, MA Krousel-Wood, LJ Launer… - Jama, 2016 - jamanetwork.com
Importance The appropriate treatment target for systolic blood pressure (SBP) in older
patients with hypertension remains uncertain. Objective To evaluate the effects of intensive (<120 …
patients with hypertension remains uncertain. Objective To evaluate the effects of intensive (<120 …
[PDF][PDF] Prevalence of dementia and major subtypes in Europe: a collaborative study of population-based cohorts
A Lobo, LJ Launer, L Fratiglioni, K Andersen… - Neurology, 2000 - researchgate.net
Article abstract: The last comparison of prevalence figures of dementia across European
studies was 10 years ago. Using studies conducted in the 1990s, the authors compare the age-…
studies was 10 years ago. Using studies conducted in the 1990s, the authors compare the age-…
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
…, AL DeStefano, AL Fitzpatrick, O Lopez, LJ Launer… - Nature …, 2011 - nature.com
We sought to identify new susceptibility loci for Alzheimer's disease through a staged
association study (GERAD+) and by testing suggestive loci reported by the Alzheimer's Disease …
association study (GERAD+) and by testing suggestive loci reported by the Alzheimer's Disease …
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment
…, RM Kirkpatrick, M Kowgier, A Latvala, LJ Launer… - science, 2013 - science.org
A genome-wide association study (GWAS) of educational attainment was conducted in a
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
[HTML][HTML] Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits
…, V Gudnason, G Eiriksdottir, ME Garcia, LJ Launer… - PLoS …, 2011 - journals.plos.org
Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common
genetic variants influencing risk are near PNPLA3. We sought to identify additional genetic …
genetic variants influencing risk are near PNPLA3. We sought to identify additional genetic …