User profiles for L. Heggelund

Lars Heggelund

MD, PhD
Verified email at uib.no
Cited by 3544

Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients

…, F Lund-Johansen, L Heggelund… - Proceedings of the …, 2020 - National Acad Sciences
Respiratory failure in the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
is hypothesized to be driven by an overreacting innate immune response, where the …

Evaluation of the effects of remdesivir and hydroxychloroquine on viral clearance in COVID-19: a randomized trial

…, Å Berg, A Johannessen, L Heggelund… - Annals of internal …, 2021 - acpjournals.org
Background: New treatment modalities are urgently needed for patients with COVID-19. The
World Health Organization (WHO) Solidarity trial showed no effect of remdesivir or …

[HTML][HTML] Distinct and early increase in circulating MMP-9 in COVID-19 patients with respiratory failure

…, P Aukrust, AM Dyrhol-Riise, L Heggelund - The Journal of …, 2020 - ncbi.nlm.nih.gov
Respiratory failure is common and the most severe complication in Coronavirus SARS-CoV-2
disease of 2019 (COVID-19)[1]. We read with much interest the recent article in Your …

Nanoproducts–what is actually available to European consumers?

SF Hansen, LR Heggelund, PR Besora… - Environmental …, 2016 - pubs.rsc.org
It remains unclear which kinds of nanoproducts are available on the European market, although
this information is a prerequisite for any kind of exposure and risk assessment. In order …

[HTML][HTML] Etiology of community-acquired pneumonia and diagnostic yields of microbiological methods: a 3-year prospective study in Norway

…, SS Frøland, P Aukrust, E Husebye, L Heggelund - BMC infectious …, 2015 - Springer
… viruses; and urine antigen assays for detection of pneumococcal and L. pneumophila antigens.
… pneumophila was positive; or real-time PCR detection of L. pneumophila or P. jirovecii in …

Hepatitis C reinfection after sustained virological response

…, H Kileng, JK Damås, J Paulsen, L Heggelund… - Journal of …, 2016 - Elsevier
Background & Aims On-going risk behaviour can lead to hepatitis C virus (HCV) reinfection
following successful treatment. We aimed to assess the incidence of persistent HCV …

Soil pH effects on the comparative toxicity of dissolved zinc, non-nano and nano ZnO to the earthworm Eisenia fetida

LR Heggelund, M Diez-Ortiz, S Lofts, E Lahive… - …, 2014 - Taylor & Francis
To determine how soil properties influence nanoparticle (NP) fate, bioavailability and toxicity,
this study compared the toxicity of nano zinc oxide (ZnO NPs), non-nano ZnO and ionic …

Elevated markers of gut leakage and inflammasome activation in COVID‐19 patients with cardiac involvement

H Hoel, L Heggelund, DH Reikvam… - Journal of internal …, 2021 - Wiley Online Library
… −1 , men: <50 y 85–249 ng L −1 ; 50–69 y 250–499 ng L −1 ; ≥70 y ≥ 500 ng L −1 ) and/or
cardiac troponins reflecting myocardial damage: troponin T (TnT) (≥14 ng mL −1 ), or TnI (…

[HTML][HTML] Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19

…, T Ueland, TE Mollnes, P Aukrust, L Heggelund… - Scientific reports, 2020 - nature.com
In SARS-CoV-2 infection there is an urgent need to identify patients that will progress to
severe COVID-19 and may benefit from targeted treatment. In this study we analyzed plasma …

[HTML][HTML] Corticosteroids and superinfections in COVID-19 patients on invasive mechanical ventilation

…, JE Berdal, MA Lehre, T Lorentsen, L Heggelund… - Journal of Infection, 2022 - Elsevier
Objectives To determine the incidence and characteristics of superinfections in mechanically
ventilated COVID-19 patients, and the impact of dexamethasone as standard therapy. …