User profiles for Laura Donahoe

Laura Donahoe

University of Toronto
Verified email at uhn.ca
Cited by 1394

[HTML][HTML] Extracorporeal life support as a bridge to lung transplantation–experience of a high-volume transplant center

K Hoetzenecker, L Donahoe, JC Yeung, S Azad… - The Journal of thoracic …, 2018 - Elsevier
Objectives Extracorporeal life support (ECLS) is increasingly used to bridge deteriorating
patients awaiting lung transplantation (LTx), however, few systematic descriptions of this …

Long-term outcomes of lung transplant with ex vivo lung perfusion

…, A Pierre, K Yasufuku, JC Yeung, L Donahoe… - JAMA …, 2019 - jamanetwork.com
Importance The mortality rate for individuals on the wait list for lung transplant is 15% to 25%,
and still only 20% of lungs from multiorgan donors are used for lung transplant. The lung …

Bleeding during critical illness: a prospective cohort study using a new measurement tool

DM Arnold, L Donahoe, FJ Clarke… - Clinical and …, 2007 - utpjournals.press
Purpose To estimate the incidence, severity, duration and consequences of bleeding during
critical illness, and to test the performance characteristics of a new bleeding assessment tool…

Prevention of viral transmission during lung transplantation with hepatitis C-viraemic donors: an open-label, single-centre, pilot trial

…, AS Slutsky, JC Yeung, L Donahoe… - The Lancet …, 2020 - thelancet.com
Background A substantial proportion of organ donors test positive for hepatitis C virus (HCV)
infection. To date, only a few studies have evaluated the safety of using lungs from these …

Association of circulating tumor DNA testing before tissue diagnosis with time to treatment among patients with suspected advanced lung cancer: the accelerate …

…, TK Waddell, K Yasufuku, G Liu, LL Donahoe… - JAMA Network …, 2023 - jamanetwork.com
Importance Liquid biopsy has emerged as a complement to tumor tissue profiling for advanced
non–small cell lung cancer (NSCLC). The optimal way to integrate liquid biopsy into the …

Surgery for malignant pleural mesothelioma after radiotherapy (SMART): final results from a single-centre, phase 2 trial

BCJ Cho, L Donahoe, PA Bradbury, N Leighl… - The Lancet …, 2021 - thelancet.com
Background A novel approach for managing malignant pleural mesothelioma, surgery for
mesothelioma after radiotherapy (SMART), consisting of a short accelerated course of high-…

[HTML][HTML] Normothermic ex vivo lung perfusion: does the indication impact organ utilization and patient outcomes after transplantation?

M Cypel, JC Yeung, L Donahoe, M Chen… - The Journal of thoracic …, 2020 - Elsevier
Background Ex vivo lung perfusion (EVLP) is being increasingly applied as a method to
evaluate and treat donor lungs for transplantation. However, with the previous limited worldwide …

[HTML][HTML] A machine-learning approach to human ex vivo lung perfusion predicts transplantation outcomes and promotes organ utilization

AT Sage, LL Donahoe, AA Shamandy… - Nature …, 2023 - nature.com
Ex vivo lung perfusion (EVLP) is a data-intensive platform used for the assessment of isolated
lungs outside the body for transplantation; however, the integration of artificial intelligence …

Initial lung transplantation experience with uncontrolled donation after cardiac death in North America

…, A Humar, J Yeung, L Donahoe… - American Journal of …, 2020 - Wiley Online Library
Uncontrolled donation after cardiac death (uDCD) has the potential to ameliorate the shortage
of suitable lungs for transplant. To date, no lung transplant data from these donors are …

Lung transplantation for cystic fibrosis

…, K Yasufuku, M de Perrot, LL Donahoe… - The Journal of Heart and …, 2020 - Elsevier
BACKGROUND The contribution of lung transplantation to the treatment of patients with end-stage
cystic fibrosis (CF) has been debated. We aimed to describe achievable outcomes …