Early life environmental control: effect on symptoms, sensitization, and lung function at age 3 years
A Woodcock, LA Lowe, CS Murray… - American journal of …, 2004 - atsjournals.org
We investigated whether environmental control during pregnancy and early life affects
sensitization and lung function at the age of 3 years. High-risk children (n = 251) were prenatally …
sensitization and lung function at the age of 3 years. High-risk children (n = 251) were prenatally …
Wheeze phenotypes and lung function in preschool children
LA Lowe, A Simpson, A Woodcock, J Morris… - American journal of …, 2005 - atsjournals.org
Distinct phenotypes can be identified in childhood wheezing illness. Within the context of a
birth cohort study, we investigated the association between preschool lung function and …
birth cohort study, we investigated the association between preschool lung function and …
Trajectories of lung function during childhood
Rationale: Developmental patterns of lung function during childhood may have major
implications for our understanding of the pathogenesis of respiratory disease throughout life. …
implications for our understanding of the pathogenesis of respiratory disease throughout life. …
The national asthma campaign Manchester asthma and allergy study
…, BM Simpson, CS Murray, L Lowe… - Pediatric Allergy and …, 2002 - Wiley Online Library
The NAC Manchester Asthma and Allergy Study is a prospective study of the development
of asthma and allergies in childhood. The subjects (995 children at age 3 years) were …
of asthma and allergies in childhood. The subjects (995 children at age 3 years) were …
Polymorphisms in A Disintegrin and Metalloprotease 33 (ADAM33) Predict Impaired Early-Life Lung Function
…, F Jury, JA Cakebread, LA Lowe… - American journal of …, 2005 - atsjournals.org
Rationale: Asthma commonly originates in early life in association with impaired lung function,
which tracks to adulthood. Objectives: Within the context of a prospective birth cohort study…
which tracks to adulthood. Objectives: Within the context of a prospective birth cohort study…
Specific airway resistance in 3-year-old children: a prospective cohort study
L Lowe, CS Murray, A Custovic, BM Simpson… - The Lancet, 2002 - thelancet.com
Background The development of a method to assess lung function in young children may
provide new insight into asthma development. Plethysmographic measurement of specific …
provide new insight into asthma development. Plethysmographic measurement of specific …
Long-term Exposure to PM10 and NO2 in Association with Lung Volume and Airway Resistance in the MAAS Birth Cohort
…, S Lindley, W Gerrard, L Lowe… - Environmental …, 2013 - ehp.niehs.nih.gov
Background: Findings from previous studies on the effects of air pollution exposure on lung
function during childhood have been inconsistent. A common limitation has been the quality …
function during childhood have been inconsistent. A common limitation has been the quality …
The role of growth and nutrition in the early origins of spirometric restriction in adult life: a longitudinal, multicohort, population-based study
…, I Kull, A Bergström, CS Murray, L Lowe… - The Lancet …, 2022 - thelancet.com
Background Spirometric restriction, defined as a reduced forced vital capacity (FVC) with a
preserved FEV 1 /FVC ratio, is associated with increased respiratory and non-respiratory …
preserved FEV 1 /FVC ratio, is associated with increased respiratory and non-respiratory …
Day-care attendance, position in sibship, and early childhood wheezing: a population-based birth cohort study
BACKGROUND: There are conflicting data on the effect of day-care attendance and position
in sibship on the development of wheezing. OBJECTIVE: To investigate the relationship …
in sibship on the development of wheezing. OBJECTIVE: To investigate the relationship …
[HTML][HTML] Diagnosis of asthma in symptomatic children based on measures of lung function: an analysis of data from a population-based birth cohort study
C Murray, P Foden, L Lowe, H Durrington… - The lancet child & …, 2017 - thelancet.com
Background Concerns have been expressed about asthma overdiagnosis. The UK National
Institute of Health and Care Excellence (NICE) proposed a new diagnostic algorithm …
Institute of Health and Care Excellence (NICE) proposed a new diagnostic algorithm …