The acute respiratory distress syndrome
LB Ware, MA Matthay - New England Journal of Medicine, 2000 - Mass Medical Soc
The acute respiratory distress syndrome is a common, devastating clinical syndrome of
acute lung injury that affects both medical and surgical patients. Since the last review of this …
acute lung injury that affects both medical and surgical patients. Since the last review of this …
Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis
…, MJ Bacchetta, JE Loyd, CM Shaver, LB Ware… - Science …, 2020 - science.org
Pulmonary fibrosis (PF) is a form of chronic lung disease characterized by pathologic epithelial
remodeling and accumulation of extracellular matrix (ECM). To comprehensively define …
remodeling and accumulation of extracellular matrix (ECM). To comprehensively define …
[HTML][HTML] Redefining critical illness
…, B Venkatesh, KR Walley, TS Walsh, LB Ware… - Nature medicine, 2022 - nature.com
Research and practice in critical care medicine have long been defined by syndromes,
which, despite being clinically recognizable entities, are, in fact, loose amalgams of …
which, despite being clinically recognizable entities, are, in fact, loose amalgams of …
Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials
…, PE Parsons, BT Thompson, LB Ware… - The Lancet …, 2014 - thelancet.com
Background Subphenotypes have been identified within heterogeneous diseases such as
asthma and breast cancer, with important therapeutic implications. We assessed whether …
asthma and breast cancer, with important therapeutic implications. We assessed whether …
[HTML][HTML] The acute respiratory distress syndrome
MA Matthay, LB Ware… - The Journal of clinical …, 2012 - Am Soc Clin Investig
… , R37HL51856, U01HL10871301, and R01HL101779 from the NHLBI; R01A1087674
and P01A1053194 from the National Institute of Allergy and Infectious Diseases), LB Ware (…
and P01A1053194 from the National Institute of Allergy and Infectious Diseases), LB Ware (…
Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome
LB Ware, MA Matthay - American journal of respiratory and critical …, 2001 - atsjournals.org
Because experimental studies have shown that intact alveolar epithelial fluid transport
function is critical for resolution of pulmonary edema and acute lung injury, we measured net …
function is critical for resolution of pulmonary edema and acute lung injury, we measured net …
The outcome of neutrophil gelatinase-associated lipocalin-positive subclinical acute kidney injury: a multicenter pooled analysis of prospective studies
…, CR Martling, P Venge, E Siew, LB Ware… - Journal of the American …, 2011 - jacc.org
Objectives : The aim of this study was to test the hypothesis that, without diagnostic changes
in serum creatinine, increased neutrophil gelatinase-associated lipocalin (NGAL) levels …
in serum creatinine, increased neutrophil gelatinase-associated lipocalin (NGAL) levels …
Acute pulmonary edema
LB Ware, MA Matthay - New England Journal of Medicine, 2005 - Mass Medical Soc
A 62-year-old man presents with a three-day history of progressive dyspnea, nonproductive
cough, and low-grade fever. His blood pressure is 100/60 mm Hg, his heart rate 110 beats …
cough, and low-grade fever. His blood pressure is 100/60 mm Hg, his heart rate 110 beats …
Comparison of the SpO2/FIO2 ratio and the PaO2/FIO2 ratio in patients with acute lung injury or ARDS
…, GR Bernard, DL Hayden, DA Schoenfeld, LB Ware… - Chest, 2007 - Elsevier
Background The diagnostic criteria for acute lung injury (ALI) and ARDS utilize the Pao 2 /fraction
of inspired oxygen (Fio 2 ) [P/F] ratio measured by arterial blood gas analysis to assess …
of inspired oxygen (Fio 2 ) [P/F] ratio measured by arterial blood gas analysis to assess …
Acute respiratory distress syndrome subphenotypes respond differently to randomized fluid management strategy
KR Famous, K Delucchi, LB Ware… - American journal of …, 2017 - atsjournals.org
Rationale: We previously identified two acute respiratory distress syndrome (ARDS) subphenotypes
in two separate randomized controlled trials with differential response to positive end…
in two separate randomized controlled trials with differential response to positive end…