[PDF][PDF] Fc effector function contributes to the activity of human anti-CTLA-4 antibodies
…, R Rosenthal, E Ghorani, I Solomon, MH Lesko… - Cancer cell, 2018 - cell.com
With the use of a mouse model expressing human Fc-gamma receptors (FcγRs), we
demonstrated that antibodies with isotypes equivalent to ipilimumab and tremelimumab mediate …
demonstrated that antibodies with isotypes equivalent to ipilimumab and tremelimumab mediate …
The first European family with gastric adenocarcinoma and proximal polyposis of the stomach: case report and review of the literature
…, S Rejchrt, M Minarik, L Benesova, M Lesko… - Gastrointestinal …, 2016 - Elsevier
Background and Aims Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS)
has to date been recognized in only 8 families worldwide. Recently, different point …
has to date been recognized in only 8 families worldwide. Recently, different point …
[HTML][HTML] Inwardly rectifying potassium channel Kir2. 1 and its “Kir-ious” regulation by protein trafficking and roles in development and disease
Potassium (K + ) homeostasis is tightly regulated for optimal cell and organismal health.
Failure to control potassium balance results in disease, including cardiac arrythmias and …
Failure to control potassium balance results in disease, including cardiac arrythmias and …
[PDF][PDF] Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors
…, I Solomon, K Joshi, L Mekkaoui, MH Lesko… - Immunity, 2017 - cell.com
CD25 is expressed at high levels on regulatory T (Treg) cells and was initially proposed as
a target for cancer immunotherapy. However, anti-CD25 antibodies have displayed limited …
a target for cancer immunotherapy. However, anti-CD25 antibodies have displayed limited …
Red blood cell transfusions and nosocomial infections in critically ill patients
…, L Manganaro, M Cytron, MF Lesko… - Critical care …, 2006 - journals.lww.com
Objective: A previous retrospective evaluation of Project Impact data demonstrated an
association between red blood cell transfusions, nosocomial infections, and poorer outcomes in …
association between red blood cell transfusions, nosocomial infections, and poorer outcomes in …
Effect of treatment with sacubitril/valsartan in patients with advanced heart failure and reduced ejection fraction: a randomized clinical trial
…, A Dirks, K Bult, E Weber, M Lesko… - JAMA …, 2022 - jamanetwork.com
Importance The use of sacubitril/valsartan is not endorsed by practice guidelines for use in
patients with New York Heart Association class IV heart failure with a reduced ejection …
patients with New York Heart Association class IV heart failure with a reduced ejection …
Using bar-code technology and medication observation methodology for safer medication administration
RD Paoletti, TM Suess, MG Lesko… - American journal of …, 2007 - academic.oup.com
Purpose. The implementation of a multidisciplinary approach to systematically decrease
medication errors through the use of observation methodology and the deployment of electronic …
medication errors through the use of observation methodology and the deployment of electronic …
Predicting outcome after severe traumatic brain injury using the serum S100B biomarker: results using a single (24 h) time-point
BACKGROUND AND OBJECTIVES: In recent years, biochemical markers have been
employed to predict the outcome of patients with traumatic brain injury (TBI). In mild TBI, S100B …
employed to predict the outcome of patients with traumatic brain injury (TBI). In mild TBI, S100B …
Vertical profile of epiphytes in a Pacific Northwest old-growth forest
…, R Harris, M Hutten, B Larson, M Lesko… - Northwest …, 1997 - rex.libraries.wsu.edu
… Each obser\,er estimated percent covet of each functional group at 5 m intervals beginning 5
m from the ground. Transects continued through thc highest 5 m nark with visible epiphytes …
m from the ground. Transects continued through thc highest 5 m nark with visible epiphytes …
Operational optimization in district heating systems with the use of thermal energy storage
The aim of this document is to present the topic of operational optimization in District
Heating (DH) systems, with special focus on different kinds of thermal energy storage. An …
Heating (DH) systems, with special focus on different kinds of thermal energy storage. An …