User profiles for M. Lesko

Michał Leśko

- Verified email at itc.pw.edu.pl - Cited by 121

Mitchell A. Lesko

- Verified email at pitt.edu - Cited by 40

[PDF][PDF] Fc effector function contributes to the activity of human anti-CTLA-4 antibodies

…, R Rosenthal, E Ghorani, I Solomon, MH Lesko… - Cancer cell, 2018 - cell.com
With the use of a mouse model expressing human Fc-gamma receptors (FcγRs), we
demonstrated that antibodies with isotypes equivalent to ipilimumab and tremelimumab mediate …

The first European family with gastric adenocarcinoma and proximal polyposis of the stomach: case report and review of the literature

…, S Rejchrt, M Minarik, L Benesova, M Lesko… - Gastrointestinal …, 2016 - Elsevier
Background and Aims Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS)
has to date been recognized in only 8 families worldwide. Recently, different point …

[HTML][HTML] Inwardly rectifying potassium channel Kir2. 1 and its “Kir-ious” regulation by protein trafficking and roles in development and disease

NA Hager, CK McAtee, MA Lesko… - Frontiers in Cell and …, 2022 - frontiersin.org
Potassium (K + ) homeostasis is tightly regulated for optimal cell and organismal health.
Failure to control potassium balance results in disease, including cardiac arrythmias and …

[PDF][PDF] Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors

…, I Solomon, K Joshi, L Mekkaoui, MH Lesko… - Immunity, 2017 - cell.com
CD25 is expressed at high levels on regulatory T (Treg) cells and was initially proposed as
a target for cancer immunotherapy. However, anti-CD25 antibodies have displayed limited …

Red blood cell transfusions and nosocomial infections in critically ill patients

…, L Manganaro, M Cytron, MF Lesko… - Critical care …, 2006 - journals.lww.com
Objective: A previous retrospective evaluation of Project Impact data demonstrated an
association between red blood cell transfusions, nosocomial infections, and poorer outcomes in …

Effect of treatment with sacubitril/valsartan in patients with advanced heart failure and reduced ejection fraction: a randomized clinical trial

…, A Dirks, K Bult, E Weber, M Lesko… - JAMA …, 2022 - jamanetwork.com
Importance The use of sacubitril/valsartan is not endorsed by practice guidelines for use in
patients with New York Heart Association class IV heart failure with a reduced ejection …

Using bar-code technology and medication observation methodology for safer medication administration

RD Paoletti, TM Suess, MG Lesko… - American journal of …, 2007 - academic.oup.com
Purpose. The implementation of a multidisciplinary approach to systematically decrease
medication errors through the use of observation methodology and the deployment of electronic …

Predicting outcome after severe traumatic brain injury using the serum S100B biomarker: results using a single (24 h) time-point

T Rainey, M Lesko, R Sacho, F Lecky, C Childs - Resuscitation, 2009 - Elsevier
BACKGROUND AND OBJECTIVES: In recent years, biochemical markers have been
employed to predict the outcome of patients with traumatic brain injury (TBI). In mild TBI, S100B …

Vertical profile of epiphytes in a Pacific Northwest old-growth forest

…, R Harris, M Hutten, B Larson, M Lesko… - Northwest …, 1997 - rex.libraries.wsu.edu
… Each obser\,er estimated percent covet of each functional group at 5 m intervals beginning 5
m from the ground. Transects continued through thc highest 5 m nark with visible epiphytes …

Operational optimization in district heating systems with the use of thermal energy storage

M Leśko, W Bujalski, K Futyma - Energy, 2018 - Elsevier
The aim of this document is to present the topic of operational optimization in District
Heating (DH) systems, with special focus on different kinds of thermal energy storage. An …