User profiles for M.R. Bonsignore

Bonsignore MR

Universitą di Palermo
Verified email at ibim.cnr.it
Cited by 13312

Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities

WT McNicholas, MR Bonsignore… - European …, 2007 - Eur Respiratory Soc
Considerable evidence is available in support of an independent association between
obstructive sleep apnoea syndrome (OSAS) and cardiovascular disease, which is particularly …

Sleep, sleep-disordered breathing and metabolic consequences

P Levy, MR Bonsignore, J Eckel - European Respiratory …, 2009 - Eur Respiratory Soc
Sleep profoundly affects metabolic pathways. In healthy subjects, experimental sleep restriction
caused insulin resistance (IR) and increased evening cortisol and sympathetic activation…

[HTML][HTML] Obstructive sleep apnea and comorbidities: a dangerous liaison

MR Bonsignore, P Baiamonte, E Mazzuca… - Multidisciplinary …, 2019 - Springer
Obstructive sleep apnea (OSA) is a highly prevalent disease, and is traditionally associated
with increased cardiovascular risk. The role of comorbidities in OSA patients has emerged …

Recommendations for the management of patients with obstructive sleep apnoea and hypertension

G Parati, C Lombardi, J Hedner, MR Bonsignore… - 2013 - Eur Respiratory Soc
This article is aimed at addressing the current state-of-the-art in epidemiology, pathophysiology,
diagnostic procedures and treatment options for appropriate management of obstructive …

Diabetes mellitus prevalence and control in sleep-disordered breathing: the European Sleep Apnea Cohort (ESADA) study

BD Kent, L Grote, S Ryan, JL Pepin, MR Bonsignore… - Chest, 2014 - Elsevier
BACKGROUND OSA is associated with an increased risk of cardiovascular morbidity. A
driver of this is metabolic dysfunction and in particular type 2 diabetes mellitus (T2DM). Prior …

Circulating haemopoietic and endothelial progenitor cells are decreased in COPD

…, G Morici, MA Vignola, MR Bonsignore - European …, 2006 - Eur Respiratory Soc
Circulating CD34+ cells are haemopoietic progenitors that may play a role in tissue repair.
No data are available on circulating progenitors in chronic obstructive pulmonary disease (…

Position paper on the management of patients with obstructive sleep apnea and hypertension: joint recommendations by the European Society of Hypertension, by the …

…, C Lombardi, J Hedner, MR Bonsignore… - Journal of …, 2012 - journals.lww.com
This article is aimed at addressing the current state of the art in epidemiology, pathophysiology,
diagnostic procedures and treatment options for appropriate management of obstructive …

Autonomic cardiac regulation in obstructive sleep apnea syndrome: evidence from spontaneous baroreflex analysis during sleep

G Parati, M Di Rienzo, MR Bonsignore… - Journal of …, 1997 - journals.lww.com
Objective To assess spontaneous baroreceptor-heart rate reflex sensitivity during sleep in
patients with obstructive sleep apnea syndrome, a condition associated with increased …

Cigarette smoke increases Toll‐like receptor 4 and modifies lipopolysaccharide‐mediated responses in airway epithelial cells

…, M Johnson, MR Bonsignore, G Bonsignore… - …, 2008 - Wiley Online Library
Airway epithelium is emerging as a regulator of innate immune responses to a variety of
insults including cigarette smoke. The main goal of this study was to explore the effects of …

Challenges and perspectives in obstructive sleep apnoea: report by an ad hoc working group of the Sleep Disordered Breathing Group of the European Respiratory …

…, CL Bassetti, MR Bonsignore… - European respiratory …, 2018 - Eur Respiratory Soc
Obstructive sleep apnoea (OSA) is a major challenge for physicians and healthcare systems
throughout the world. The high prevalence and the impact on daily life of OSA oblige …