Coronavirus disease (COVID-19) has generated interest in the assessment of systemic
immune status, but existing knowledge about mucosal immunity is clearly insufficient to …

To date, the advantage of adjuvanted over non-adjuvanted vaccines in the specific antibodies
formation is proved. However, cellular mechanisms, including parameters of the innate …

Pregnancy is a condition of modulated immune suppression, so this group of patients has
increased risk of infectious diseases. Trivalent subunit vaccines, unadjusted Agrippal S1 (…

Background Although extensive research has been conducted on the role of local immunity
in patients with SARS-CoV-2, little is known about the production and concentrations of …

Background. Influenza prophylaxis with the use of quadrivalent vaccines (QIV) is increasingly
being introduced into healthcare practice. Methods. In total, 32 healthy adults and 6 …

Pregnant women are risk group for influenza infection. Results of new subunit vaccines
application have not been studied enough. Prospective, randomized, open-label comparative …

Background: Recent addition to vaccines of adjuvants has been actively used to enhance
the immunogenicity. However, the use of adjuvants for the development of quadrivalent …

Background: In the last decade, adjuvant-containing vaccines, exerting different effects on the
immune system, including the production of cytokines, which are one of the most important …

Background: for the first time, the effect of one and two doses of adjuvanted influenza
vaccines on toll-like receptors (TLRs) in patients with common variable immunodeficiency (CVID) …

Purpose Understanding the relationship between patient immune characteristics, disease
severity, and mortality represents a critical step in the fight against COVID-19. Elevated levels …