The TB portals: an open-access, web-based platform for global drug-resistant-tuberculosis data sharing and analysis
…, C Ene, S Vashakidze, N Shubladze… - Journal of clinical …, 2017 - Am Soc Microbiol
The TB Portals program is an international consortium of physicians, radiologists, and
microbiologists from countries with a heavy burden of drug-resistant tuberculosis working with …
microbiologists from countries with a heavy burden of drug-resistant tuberculosis working with …
[HTML][HTML] Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections
M Moreno-Molina, N Shubladze, I Khurtsilava… - Nature …, 2021 - nature.com
Polyclonal infections occur when at least two unrelated strains of the same pathogen are
detected in an individual. This has been linked to worse clinical outcomes in tuberculosis, as …
detected in an individual. This has been linked to worse clinical outcomes in tuberculosis, as …
[HTML][HTML] High prevalence of multidrug-resistant tuberculosis in Georgia
…, N Volkova, E Kourbatova, T Jibuti, N Shubladze… - International Journal of …, 2008 - Elsevier
BACKGROUND: Tuberculosis (TB) has emerged as a serious public health problem in the
country of Georgia. However, little or no data exist on rates and risk factors for drug-resistant …
country of Georgia. However, little or no data exist on rates and risk factors for drug-resistant …
[HTML][HTML] Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment
…, S Sengstake, T Shinnick, N Shubladze… - European …, 2022 - Eur Respiratory Soc
Inappropriately high breakpoints have resulted in systematic false-susceptible AST results
to anti-TB drugs. MIC, PK/PD and clinical outcome data should be combined when setting …
to anti-TB drugs. MIC, PK/PD and clinical outcome data should be combined when setting …
[HTML][HTML] Impact of the COVID-19 pandemic on tuberculosis national reference laboratory services in the WHO European Region, March to November 2020
FP Maurer, N Shubladze, G Kalmambetova… - …, 2021 - eurosurveillance.org
We assessed the impact of COVID-19 on diagnostic services for tuberculosis (TB) by national
reference laboratories in the WHO European Region. Of 35 laboratories, 30 reported …
reference laboratories in the WHO European Region. Of 35 laboratories, 30 reported …
Tuberculosis, HIV, and viral hepatitis diagnostics in eastern Europe and central Asia: high time for integrated and people-centred services
…, G Kalmambetova, E Noroc, N Shubladze… - The Lancet Infectious …, 2020 - thelancet.com
Globally, high rates (and in the WHO European region an increasing prevalence) of co-infection
with tuberculosis and HIV and HIV and hepatitis C virus exist. In eastern European and …
with tuberculosis and HIV and HIV and hepatitis C virus exist. In eastern European and …
[HTML][HTML] Integrated use of laboratory services for multiple infectious diseases in the WHO European Region during the COVID-19 pandemic and beyond
…, S Ehsani, M Stanojevic, N Shubladze… - …, 2022 - eurosurveillance.org
Technical advances in diagnostic techniques have permitted the possibility of multi-disease-based
approaches for diagnosis and treatment monitoring of several infectious diseases, …
approaches for diagnosis and treatment monitoring of several infectious diseases, …
Impact of adjuvant therapeutic surgery on the health-related quality of life of pulmonary tuberculosis patients
…, A Despuig, N Tukvadze, N Shubladze… - ERJ Open …, 2020 - Eur Respiratory Soc
This study aimed to determine the health-related quality of life (HRQoL) of patients with
pulmonary tuberculosis (TB) and to assess its change after a therapeutic surgical procedure. In …
pulmonary tuberculosis (TB) and to assess its change after a therapeutic surgical procedure. In …
[HTML][HTML] Diagnostic Capacities for Multidrug-Resistant Tuberculosis in the World Health Organization European Region: Action is Needed by all Member States
FP Maurer, N Shubladze, G Kalmambetova… - The Journal of Molecular …, 2022 - Elsevier
The World Health Organization (WHO) recently revised its guidelines for rapid diagnosis of
drug-resistant tuberculosis (TB). This study aimed to investigate if TB reference diagnostic …
drug-resistant tuberculosis (TB). This study aimed to investigate if TB reference diagnostic …
[HTML][HTML] Retrospective study of clinical and lesion characteristics of patients undergoing surgical treatment for Pulmonary Tuberculosis in Georgia
…, S Gogishvili, K Nikolaishvili, N Shubladze… - International Journal of …, 2017 - Elsevier
Objectives Our aim was to retrospectively compare clinical data and characteristics of removed
lesions of the cohort of patients undergoing therapeutical surgery for their tuberculosis. …
lesions of the cohort of patients undergoing therapeutical surgery for their tuberculosis. …