Oxidative stress is involved in the aetiology of defective embryo development. Reactive
oxygen species (ROS) may originate from embryo metabolism and/or embryo surroundings. …

To combat the threat to human health and biosecurity from antimicrobial resistance, an
understanding of its mechanisms and drivers is needed. Emergence of antimicrobial resistance in …

Visceral leishmaniasis is common in less developed countries, with an estimated 500 000
new cases each year. Because of the diversity of epidemiological situations, no single …

Background Artemisinin resistance in Plasmodium falciparum has emerged in Southeast Asia
and now poses a threat to the control and elimination of malaria. Mapping the geographic …

Background In patients who have chronic heart failure with reduced left ventricular ejection
fraction, severe secondary mitral-valve regurgitation is associated with a poor prognosis. …

Background Trials of patent foramen ovale (PFO) closure to prevent recurrent stroke have
been inconclusive. We investigated whether patients with cryptogenic stroke and …

Background Experimental and clinical evidence suggests that cyclosporine may attenuate
reperfusion injury and reduce myocardial infarct size. We aimed to test whether cyclosporine …

The field of biodegradable polymers is a fast growing area of polymer science because of
the interest of such compounds for temporary surgical and pharmacological applications. …

Rho kinases (ROCKs) are the first and the best-characterized effectors of the small G-protein
RhoA. In addition to their effect on actin organization, or through this effect, ROCKs have …

… We aimed to assess the spread of artemisinin-resistant P falciparum in Myanmar by
determining the relative prevalence of P falciparum parasites carrying K13-propeller mutations. …