SMART-COP: a tool for predicting the need for intensive respiratory or vasopressor support in community-acquired pneumonia

…, P Holmes, DS Obrosky, P Peyrani… - Clinical infectious …, 2008 - academic.oup.com
Background . Existing severity assessment tools, such as the pneumonia severity index (PSI)
and CURB-65 (tool based on confusion, urea level, respiratory rate, blood pressure, and …

Adults hospitalized with pneumonia in the United States: incidence, epidemiology, and mortality

JA Ramirez, TL Wiemken, P Peyrani… - Clinical Infectious …, 2017 - academic.oup.com
Background Understanding the burden of community-acquired pneumonia (CAP) is critical
to allocate resources for prevention, management, and research. The objectives of this study …

A worldwide perspective of atypical pathogens in community-acquired pneumonia

…, JT Summersgill, AS LaJoie, P Peyrani… - American journal of …, 2007 - atsjournals.org
Rationale: Controversy still exists in the international literature regarding the need to use
antimicrobials covering atypical pathogens when initially treating hospitalized patients with …

Implementation of guidelines for management of possible multidrug-resistant pneumonia in intensive care: an observational, multicentre cohort study

…, JE Mangino, MJ Zervos, P Peyrani… - The Lancet infectious …, 2011 - thelancet.com
Background The American Thoracic Society and Infectious Diseases Society of America
provide guidelines for management of hospital-acquired, ventilator-associated, and health-care-…

[HTML][HTML] Understanding the roles of cytokines and neutrophil activity and neutrophil apoptosis in the protective versus deleterious inflammatory response in pneumonia

…, SM Uriarte, MJ Rane, P Duvvuri, P Peyrani… - International Journal of …, 2013 - Elsevier
Inflammation is a double-edged sword in the outcome of pneumonia. On the one hand, an
effective and timely inflammatory response is required to eliminate the invading respiratory …

Acute myocardial infarction in hospitalized patients with community-acquired pneumonia

…, S Aliberti, M Mirsaeidi, P Peyrani… - Clinical infectious …, 2008 - academic.oup.com
Background. An epidemiological link between respiratory infection and acute myocardial
infarction (AMI) has been suggested, and recent data indicate that there is an association …

Thrombocytopenia and thrombocytosis at time of hospitalization predict mortality in patients with community-acquired pneumonia

M Mirsaeidi, P Peyrani, S Aliberti, G Filardo, J Bordon… - Chest, 2010 - Elsevier
Background Platelets are inflammatory cells with an important role in antimicrobial host
defenses. We speculate that an abnormal platelet count may be a marker of severity in patients …

Improving outcomes in elderly patients with community-acquired pneumonia by adhering to national guidelines: Community-Acquired Pneumonia Organization …

…, AS LaJoie, GN Brock, P Peyrani… - Archives of internal …, 2009 - jamanetwork.com
Background To define whether elderly patients hospitalized with community-acquired
pneumonia (CAP) had better outcomes if they were treated with empirical antimicrobial therapy …

Incidence of nephrotoxicity and association with vancomycin use in intensive care unit patients with pneumonia: retrospective analysis of the IMPACT-HAP Database

EL Cano, NZ Haque, VL Welch, CM Cely, P Peyrani… - Clinical …, 2012 - Elsevier
BACKGROUND: The 2005 guidelines from the American Thoracic Society and the Infectious
Diseases Society of America recommend vancomycin trough levels of 15 to 20 mg/L for the …

Effectiveness of 13-valent pneumococcal conjugate vaccine against hospitalization for community-acquired pneumonia in older US adults: a test-negative design

…, BD Gessner, RM Carrico, P Peyrani… - Clinical Infectious …, 2018 - academic.oup.com
Background Following universal recommendation for use of 13-valent pneumococcal conjugate
vaccine (PCV13) in US adults aged ≥65 years in September 2014, we conducted the …