A statin in the treatment of heart failure? Controlled rosuvastatin multinational study in heart failure (CORONA): study design and baseline characteristics

…, F Waagstein, H Wedel, P Wessman… - European journal of …, 2005 - Wiley Online Library
Background: Previous prospective outcome studies of statins have not provided any guidance
on benefit‐risk in patients with heart failure. Aim: The primary objective is to determine …

Tralokinumab for severe, uncontrolled asthma (STRATOS 1 and STRATOS 2): two randomised, double-blind, placebo-controlled, phase 3 clinical trials

…, U Sjöbring, AM Péterffy, P Wessman… - The Lancet …, 2018 - thelancet.com
Background Tralokinumab is an anti-interleukin-13 human monoclonal antibody developed
for the treatment of severe, uncontrolled asthma. These clinical trials aimed to assess the …

Corticosteroid tapering with benralizumab treatment for eosinophilic asthma: PONENTE Trial

…, LG Heaney, M Gurnell, P Wessman… - ERJ open …, 2019 - Eur Respiratory Soc
Benralizumab is an interleukin-5 receptor α-directed cytolytic monoclonal antibody
approved in several countries for the add-on maintenance treatment of patients with severe …

[HTML][HTML] The risk of revision following total hip arthroplasty in patients with inflammatory bowel disease, a registry based study

MM Moran, P Wessman, O Rolfson, DD Bohl… - Plos one, 2021 - journals.plos.org
Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the intestinal
tract and is associated with decreased bone mineral density. IBD patients are at higher risk of …

A nonsteroidal glucocorticoid receptor agonist inhibits allergen-induced late asthmatic responses

…, V Swystun, CK Mårdh, P Wessman… - American Journal of …, 2015 - atsjournals.org
Rationale: Effective antiinflammatory therapies are needed for the treatment of asthma, but
preferably without the systemic adverse effects of glucocorticosteroids. Objectives: We …

Safety and tolerability of an immediate-release formulation of the oral direct thrombin inhibitor AZD0837 in the prevention of stroke and systemic embolism in patients …

…, A Tveit, E Jensen, P Wessman… - Thrombosis and …, 2010 - thieme-connect.com
AZD0837 is an investigational oral anticoagulant which is converted to the active form, AR-H067637,
a selective direct thrombin inhibitor. The present study, a multicentre, randomised, …

[HTML][HTML] Reduced risk of clinically important deteriorations by ICS in COPD is eosinophil dependent: a pooled post-hoc analysis

…, C Jenkins, S Peterson, T Bengtsson, P Wessman… - Respiratory …, 2020 - Springer
Background Clinically Important Deterioration (CID) is a novel composite measure to
assess treatment effect in chronic obstructive pulmonary disease (COPD). We examined the …

Some Principles for surveillance adopted for multivariate processes with a common change point

P Wessman - Communications in Statistics-Theory and Methods, 1998 - Taylor & Francis
The surveillance of multivariate processes has received growing attention during the last
decade. Several generalizations of well-known methods such as Shewhart, CUSUM and …

[HTML][HTML] DIALIZE China: a phase IIIb, randomized, placebo-controlled study to reduce predialysis hyperkalemia with sodium zirconium cyclosilicate in Chinese patients

…, L Zuo, X Meng, Z Chang, J Zhao, P Wessman… - Clinical Therapeutics, 2023 - Elsevier
Purpose The DIALIZE China study (Reduce Incidence of Pre-Dialysis Hyperkalaemia With
Sodium Zirconium Cyclosilicate in Chinese Subjects) (NCT04217590) evaluated sodium …

The trajectory of renal function following mechanical circulatory support and subsequent heart transplantation

SE Bartfay, O Kolsrud, P Wessman… - ESC Heart …, 2022 - Wiley Online Library
Aim Patients with advanced heart failure (HF) frequently suffer from renal insufficiency. The
impact of durable mechanical circulatory support (MCS) and subsequent heart …