[HTML][HTML] Low and high serum IgG associates with respiratory infections in a young and working age population

P Holma, P Pesonen, MK Karjalainen, MR Järvelin… - …, 2023 - thelancet.com
Background We investigated health consequences and genetic properties associated with
serum IgG concentration in a young and working age general population. Methods Northern …

[HTML][HTML] 52-year follow-up of a birth cohort reveals a high pneumonia incidence among young men

P Holma, P Pesonen, O Mustonen… - ERJ Open …, 2022 - Eur Respiratory Soc
Background Knowledge of pneumonia incidence and risk factors in adults is mainly based
on clinical studies of selected patient data and registers with ageing populations. Prospective …

Serum Immunoglobulin Levels in Group E of Chronic obstructive pulmonary disease: Insights for Clinical Management and Immunoglobulin Therapy Strategies

CN Hai, TT Ba, TB Duc, CH Xuan, TV Manh - 2024 - researchsquare.com
Objective The objective of this study was to describe serum immunoglobulin concentrations
and clinical, subclinical characteristics in patients with group E of Chronic obstructive …

[HTML][HTML] Effect of remdesivir post hospitalization for COVID-19 infection from the randomized SOLIDARITY Finland trial

OPO Nevalainen, S Horstia, S Laakkonen… - Nature …, 2022 - nature.com
We report the first long-term follow-up of a randomized trial (NCT04978259) addressing the
effects of remdesivir on recovery (primary outcome) and other patient-important outcomes …

[PDF][PDF] Adaptation in triadic business relationship settings: A study in corporate travel management

A Holma - 2009 - helda.helsinki.fi
… I am grateful to Virpi, for being a friend, a fellow student and a business colleague to exchange
thoughts with in different phases of life, and to Pia for taking me out to refresh my thought …

Colonic methane production modifies gastrointestinal toxicity associated with adjuvant 5-fluorouracil chemotherapy for colorectal cancer

R Holma, R Korpela, U Sairanen, M Blom… - Journal of Clinical …, 2013 - journals.lww.com
Background: Adjuvant 5-fluorouracil chemotherapy reduces recurrences in colorectal cancer,
but causes severe gastrointestinal toxicity, partly related to disturbed intestinal microbiota. …

Colonic methanogenesis in vivo and in vitro and fecal pH after resection of colorectal cancer and in healthy intact colon

R Holma, P Osterlund, U Sairanen, M Blom… - International journal of …, 2012 - Springer
Purpose We compared colonic methanogenesis in vivo and in vitro as well as fecal pH in
healthy subjects and in patients with resected colorectal cancer thus without the possible …

[HTML][HTML] Consumption of lactose, other FODMAPs and diarrhoea during adjuvant 5-fluorouracil chemotherapy for colorectal cancer

R Holma, R Laatikainen, H Orell, H Joensuu… - Nutrients, 2020 - mdpi.com
Chemotherapy-induced mucosal injury of the small intestine may interfere with the enzymes
and transporters responsible for the hydrolysis and absorption of dietary carbohydrates …

P2RX7 gene is associated consistently with mood disorders and predicts clinical outcome in three clinical cohorts

…, P Arvilommi, I Holma, M Holma… - American Journal of …, 2011 - Wiley Online Library
We investigated the effect of nine candidate genes on risk for mood disorders, hypothesizing
that predisposing gene variants not only elevate the risk for mood disorders but also result …

Social media and small entrepreneurial firms' internationalization

…, L Haapanen, S Holma - … Social Media and …, 2020 - Springer
Small entrepreneurial firms often need to be quite creative when allocating and deploying
their limited resources. Especially in grasping international opportunities, social media …