Background The multiple breath nitrogen washout (N 2 MBW) technique is increasingly
used to assess the degree of ventilation inhomogeneity in school-aged children with lung …

Asthma is a chronic condition with unknown pathogenesis, and recent evidence suggests that
enhanced airway epithelial chloride (Cl – ) secretion plays a role in the disease. However, …

The airway epithelium is a central effector tissue in allergic inflammation and T-helper cell (Th)
type 2-driven epithelial responses, such as mucus hypersecretion contribute to airflow …

The nitrogen (N 2 ) multiple-breath washout (MBW) technique is a lung function test used to
assess ventilation distribution and lung volumes. The lung clearance index (LCI) is a marker …

It is not known at what age lung function impairment may arise in children with cystic fibrosis
(CF). We assessed lung function shortly after birth in infants with CF diagnosed by newborn …

Between March and April 2020, Cyprus and Greece health authorities enforced three escalated
levels of public health interventions to control the COVID-19 pandemic. We quantified …

(1) Background: Stereological estimations significantly contributed to our understanding of
lung anatomy and physiology. Taking stereology fully 3-dimensional facilitates the estimation …

Exhaled nitric oxide (FE NO ) is a well-known, non-invasive airway biomarker. In patients
with Cystic Fibrosis (CF) FE NO is decreased. To understand if reduced FE NO is primary …

Objective To test whether low variability of tidal volume (V T ) and capnographic indices are
predictive of subsequent respiratory morbidity in preterm infants. Study design In a birth …

Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterised by impaired mucociliary
clearance leading to irreversible lung damage. In contrast to other rare lung diseases …