Central obesity is increasingly recognized as a risk factor for atherosclerosis and type 2
diabetes mellitus. Here we present a hypothesis that may explain the excess atherosclerosis, …

Antiproteinase 3- and antimyeloperoxidase-associated vasculitis. Wegener's granulomatosis,
microscopic polyangiitis, and idiopathic pauci-immune necrotizing crescentic …

Objective: In patients with essential hypertension, defects in both the metabolic and
vascular actions of insulin have been described. Impaired microvascular function, a well-established …

Capillary rarefaction occurs in many tissues in patients with essential hypertension and may
contribute to an increased vascular resistance and impaired muscle metabolism. …

Background—A strong but presently unexplained inverse association between blood pressure
and insulin sensitivity has been reported. Microvascular vasodilator capacity may be a …

C-reactive protein is associated with renal function abnormalities in a non-diabetic population.
Background C-reactive protein (CRP) has recently been introduced in cardiovascular …

Chronic renal transplant dysfunction (CRTD) remains a leading cause of renal allograft loss.
Evidence suggests that immunological and ischemic insults are mainly associated with …

Background. Chronic transplant dysfunction is characterized by renal function decline and
proteinuria. Kidney injury molecule (KIM)-1, a transmembrane tubular protein with unknown …

OBJECTIVE: Low muscle mass often indicates poor health, but the relation with cardiovascular
disease (CVD) is unknown. Skeletal muscles are responsible for approximately 75% of …

Baroreceptor reflex sensitivity (BRS) has been found lower and heart rate variability (HRV)
parasympathetic markers have been found higher in healthy women than in healthy men. …