[HTML][HTML] A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer

…, RB Livingston, NE Davidson… - … England Journal of …, 2003 - Mass Medical Soc
Background In hormone-dependent breast cancer, five years of postoperative tamoxifen
therapy — but not tamoxifen therapy of longer duration — prolongs disease-free and overall …

Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA. 17

…, RB Livingston, NE Davidson… - Journal of the …, 2005 - academic.oup.com
Background: Most recurrences in women with breast cancer receiving 5 years of adjuvant
tamoxifen occur after 5 years. The MA.17 trial, which was designed to determine whether …

Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study

…, G Pasvol, A Lalvani, D Wright, M Latif, RN Davidson - The Lancet, 2000 - thelancet.com
Robert Wilkinson and Robert Davidson had the idea for the study and supervised its design,
execution, and analysis. Martin Llewelyn and Robert Wilkinson provided the clinical data …

High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial

…, JC Moore-Gillon, M Darmalingam, RN Davidson… - The Lancet, 2011 - thelancet.com
Background Vitamin D was used to treat tuberculosis in the pre-antibiotic era, and its
metabolites induce antimycobacterial immunity in vitro. Clinical trials investigating the effect of …

A single dose of vitamin D enhances immunity to mycobacteria

…, BM Hall, GE Packe, RN Davidson… - American journal of …, 2007 - atsjournals.org
Rationale: Vitamin D was used to treat tuberculosis (TB) in the preantibiotic era. Prospective
studies to evaluate the effect of vitamin D supplementation on antimycobacterial immunity …

IFN-γ-and TNF-independent vitamin D-inducible human suppression of mycobacteria: the role of cathelicidin LL-37

…, K Skolimowska, RN Davidson… - The Journal of …, 2007 - journals.aai.org
Vitamin D deficiency is associated with susceptibility to tuberculosis, and its biologically
active metabolite, 1α, 25 dihydroxyvitamin D 3 (1α, 25 (OH) 2 D 3), has pleiotropic immune …

[HTML][HTML] Neutrophil-mediated innate immune resistance to mycobacteria

…, N Nawroly, GE Packe, RN Davidson… - The Journal of …, 2007 - Am Soc Clin Investig
Neutrophils contain antimicrobial peptides with antituberculous activity, but their contribution
to immune resistance to tuberculosis (TB) infection has not been previously investigated to …

Direct ex vivo analysis of antigen-specific IFN-γ-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and …

…, P Klenerman, H McShane, RN Davidson… - The Journal of …, 2001 - journals.aai.org
The wide spectrum of clinical outcomes following infection with Mycobacterium tuberculosis
is largely determined by the host immune response; therefore, we studied several clinically …

Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment

…, M Darmalingam, RN Davidson… - Proceedings of the …, 2012 - National Acad Sciences
Calcidiol, the major circulating metabolite of vitamin D, supports induction of pleiotropic
antimicrobial responses in vitro. Vitamin D supplementation elevates circulating calcidiol …

Influence of polymorphism in the genes for the interleukin (IL)-1 receptor antagonist and IL-1β on tuberculosis

…, G Pasvol, G Snounou, RN Davidson… - The Journal of …, 1999 - rupress.org
Several lines of evidence suggest that host genetic factors controlling the immune response
influence infection by Mycobacterium tuberculosis. The proinflammatory cytokine interleukin …