User profiles for Ronan MacLoughlin

Ronan MacLoughlin

Head of R&D, Science and Emerging Technologies, Aerogen
Verified email at aerogen.com
Cited by 2935

Reducing aerosol-related risk of transmission in the era of COVID-19: an interim guidance endorsed by the International Society of Aerosols in Medicine

…, PJ Kuehl, S Häussermann, R MacLoughlin… - Journal of aerosol …, 2020 - liebertpub.com
National and international guidelines recommend droplet/airborne transmission and contact
precautions for those caring for coronavirus disease 2019 (COVID-19) patients in …

[HTML][HTML] Polysaccharide-based nanomedicines targeting lung cancer

…, SI Alzarea, DK Chellappan, SK Singh, R MacLoughlin… - Pharmaceutics, 2022 - mdpi.com
A primary illness that accounts for a significant portion of fatalities worldwide is cancer.
Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer …

Emerging role of exosomes as biomarkers in cancer treatment and diagnosis

…, M Radfar, F Omidi, R MacLoughlin… - Critical reviews in …, 2022 - Elsevier
Cancer is a leading cause of death worldwide and cancer incidence and mortality are rapidly
growing. These massive amounts of cancer patients require rapid diagnosis and efficient …

[HTML][HTML] Magnetic core-shell nanoparticles for drug delivery by nebulization

…, T Doody, C McAtamney, R MacLoughlin… - Journal of …, 2013 - Springer
Background Aerosolized therapeutics hold great potential for effective treatment of various
diseases including lung cancer. In this context, there is an urgent need to develop novel …

Nanoparticle-based drug delivery: case studies for cancer and cardiovascular applications

…, E Keehan, M Howe, C Duffy, R MacLoughlin - Cellular and Molecular …, 2012 - Springer
Nanoparticles (NPs) comprised of nanoengineered complexes are providing new opportunities
for enabling targeted delivery of a range of therapeutics and combinations. A range of …

Rutin loaded liquid crystalline nanoparticles inhibit non-small cell lung cancer proliferation and migration in vitro

…, G Gupta, K Anand, SK Singh, NK Jha, R MacLoughlin… - Life sciences, 2021 - Elsevier
Non-small cell lung cancer (NSCLC) is one of the major causes of cancer-related mortality
globally. Despite the availability of therapeutic options, the improvement in patient survival is …

[HTML][HTML] Berberine-loaded liquid crystalline nanoparticles inhibit non-small cell lung cancer proliferation and migration in vitro

…, T Madheswaran, R MacLoughlin… - … Science and Pollution …, 2022 - Springer
Non-small cell lung cancer (NSCLC) is reported to have a high incidence rate and is one of
the most prevalent types of cancer contributing towards 85% of all incidences of lung cancer. …

[HTML][HTML] Attenuation of cigarette-smoke-induced oxidative stress, senescence, and inflammation by berberine-loaded liquid crystalline nanoparticles: in vitro study in …

…, G Gupta, PR Wich, S Nammi, R MacLoughlin… - Antioxidants, 2022 - mdpi.com
Cigarette smoke is considered a primary risk factor for chronic obstructive pulmonary disease.
Numerous toxicants present in cigarette smoke are known to induce oxidative stress and …

[HTML][HTML] Lipid Nanoparticles as Promising Carriers for mRNA Vaccines for Viral Lung Infections

…, A Kamedi, AO Neill, R MacLoughlin… - Pharmaceutics, 2023 - mdpi.com
In recent years, there has been an increase in deaths due to infectious diseases, most notably
in the context of viral respiratory pathogens. Consequently, the focus has shifted in the …

Chemical design of both a glutathione-sensitive dimeric drug guest and a glucose-derived nanocarrier host to achieve enhanced osteosarcoma lung metastatic …

…, AS Butters, G Akabani, R MacLoughlin… - Journal of the …, 2018 - ACS Publications
Although nanomedicines have been pursued for nearly 20 years, fundamental chemical
strategies that seek to optimize both the drug and drug carrier together in a concerted effort …