Asymptomatic HIV-infected Individuals on Antiretroviral Therapy Exhibit Impaired Lung CD4+ T-Cell Responses to Mycobacteria

…, L Afran, AM Kankwatira, RD Malamba… - American journal of …, 2014 - atsjournals.org
Rationale: HIV-infected persons on antiretroviral therapy (ART) remain at higher risk of
pulmonary tuberculosis (TB) than HIV-uninfected individuals. This increased susceptibility may …

Intrapulmonary pharmacokinetics of first-line anti-tuberculosis drugs in Malawian patients with tuberculosis

…, M Chasweka, A Chitani, RD Malamba… - Clinical Infectious …, 2021 - academic.oup.com
Background Further work is required to understand the intrapulmonary pharmacokinetics of
first-line anti-tuberculosis drugs. This study aimed to describe the plasma and …

HIV-associated disruption of lung cytokine networks is incompletely restored in asymptomatic HIV-infected Malawian adults on antiretroviral therapy

…, DH Banda, AM Kankwatira, RD Malamba… - ERJ open …, 2017 - Eur Respiratory Soc
The lung is the site most commonly affected by infectious and non-infectious complications
of HIV infection [1], even in individuals on effective antiretroviral therapy (ART). HIV infection …

[HTML][HTML] Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults

…, DH Banda, N Jambo, AM Kankwatira, RD Malamba… - Journal of Infection, 2018 - Elsevier
Objective We explored if HIV infection is associated with impaired T-Helper 17 responses
against Streptococcus pneumoniae in the lung. Methods We recruited 30 HIV-uninfected …

[HTML][HTML] Intracellular survival of Streptococcus pneumoniae in human alveolar macrophages is augmented with HIV infection

…, Z Jasiunaite, C Mkandawire, R Malamba… - Frontiers in …, 2022 - frontiersin.org
People Living with HIV (PLHIV) are at an increased risk of pneumococcal pneumonia than
HIV-uninfected adults, but the reasons for this are still not well understood. We investigated …

[HTML][HTML] Alcohol consumption and oesophageal squamous cell cancer risk in east Africa: findings from the large multicentre ESCCAPE case-control study in Kenya …

…, M Suwedi, T Solomon, R Malamba… - The Lancet Global …, 2022 - thelancet.com
Background The contribution of alcohol to the large burden of oesophageal squamous cell
carcinoma (ESCC) in east Africa remains uncertain and difficult to assess owing to complex …

Wood smoke exposure, poverty and impaired lung function in Malawian adults

…, S Semple, F Kalambo, R Malamba… - … of tuberculosis and …, 2011 - ingentaconnect.com
… MÉTHODES : Nous avons fait l’hypothèse que l’exposition déclarée à la fumée de bois par
comparaison à la fumée de charbon serait en association avec une réduction de la volume …

[HTML][HTML] Inhaled delivery of 23-valent pneumococcal polysaccharide vaccine does not result in enhanced pulmonary mucosal immunoglobulin responses

SB Gordon, R Malamba, N Mthunthama, ER Jarman… - Vaccine, 2008 - Elsevier
We compared the effect of intramuscular vs. inhaled 23-valent pneumococcal capsular
polysaccharide vaccine (23-PPV) on pulmonary mucosal immunoglobulin levels. …

[HTML][HTML] Characterising B cell numbers and memory B cells in HIV infected and uninfected Malawian adults

H Longwe, S Gordon, R Malamba, N French - BMC infectious diseases, 2010 - Springer
… These data are consistent with findings reported by De Milito et al. who suggested that loss of
memory B cells might occur early after … Herbert Longwe & Rose MalambaRose Malamba

Biomass fuel use and indoor air pollution in homes in Malawi

…, F Kalambo, A Suseno, R Malamba… - Occupational and …, 2009 - oem.bmj.com
Background: Air pollution from biomass fuels in Africa is a significant cause of mortality and
morbidity both in adults and children. The work describes the nature and quantity of smoke …