Decreases in melatonin production in human and animals are known to be caused by
environmental lighting, especially short-wavelength lighting (between 470 and 525 nm). We …

Systemic lupus erythematosus (SLE) is a genetically complex disease with heterogeneous
clinical manifestations. A polymorphism in the STAT4 gene has recently been established as …

A substantial genetic contribution to systemic lupus erythematosus (SLE) risk is conferred by
major histocompatibility complex (MHC) gene(s) on chromosome 6p21. Previous studies in …

Background Obstructive sleep apnea (OSA) is a major risk factor for perioperative adverse
events. However, no screening tool for OSA has been validated in surgical patients. This …

Objective There is a need to characterize exposures associated with the pathogenesis of
systemic lupus erythematosus (SLE). In this pilot study, we explore a hypothesis‐free approach …

Objective To provide evidence‐based recommendations and expert guidance for the
management of antineutrophil cytoplasmic antibody–associated vasculitis (AAV), including …

Background Because of the high prevalence of obstructive sleep apnea (OSA) and its
adverse impact on perioperative outcome, a practical screening tool for surgical patients is …

Objective To provide evidence‐based recommendations and expert guidance for the
management of giant cell arteritis (GCA) and Takayasu arteritis (TAK) as exemplars of large vessel …

BACKGROUND: Obstructive sleep apnea (OSA) is present in a significant proportion of the
population, but the majority of patients remain undiagnosed. It is crucial that …

Background Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease in
which the risk of disease is influenced by complex genetic and environmental contributions. …