Phosphodiesterase 5 inhibitor treatment and survival in interstitial lung disease pulmonary hypertension: a Bayesian retrospective observational cohort study

…, C McCabe, K Dimopoulos, I Stewart, S Bax… - …, 2023 - Wiley Online Library
Background and Objective Pulmonary hypertension is a life‐limiting complication of interstitial
lung disease (ILD‐PH). We investigated whether treatment with phosphodiesterase 5 …

Pulmonary hypertension in interstitial lung disease: limitations of echocardiography compared to cardiac catheterization

…, PM George, SLF Walsh, J Jacob, L Price, S Bax… - …, 2018 - Wiley Online Library
Background and objective In interstitial lung disease (ILD), pulmonary hypertension (PH) is
a major adverse prognostic determinant. Transthoracic echocardiography (TTE) is the most …

Right ventricular to left ventricular ratio at CT pulmonary angiogram predicts mortality in interstitial lung disease

S Bax, J Jacob, R Ahmed, C Bredy, K Dimopoulos… - Chest, 2020 - Elsevier
Background Patients with interstitial lung disease (ILD) may develop pulmonary hypertension
(PH), often disproportionate to the severity of the ILD. The right ventricular to left ventricular …

A stepwise composite echocardiographic score predicts severe pulmonary hypertension in patients with interstitial lung disease

S Bax, C Bredy, A Kempny, K Dimopoulos… - ERJ open …, 2018 - Eur Respiratory Soc
European Respiratory Society (ERS) guidelines recommend the assessment of patients
with interstitial lung disease (ILD) and severe pulmonary hypertension (PH), as defined by a …

Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: a general mechanism to accumulate effector cells in inflammation

…, MH Schöni, K Blaser, HU Simon - Proceedings of the …, 1999 - National Acad Sciences
… Moreover, Bax-deficient neutrophils generated by using Bax antisense … for a role of Bax
as a pro-apoptotic molecule in these cells. Interestingly, the Bax gene was reexpressed in Bax-…

[PDF][PDF] The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

…, Y Chen, M Wei, VM Eng, DM Adelman, MC Simon… - Molecular cell, 2000 - cell.com
… However, mice lacking bax display limited phenotypic abnormalities. As presented here, …
were mated to Bax-deficient mice to create mice lacking both genes, the majority of bax −/− bak …

Expression of the Apoptosis‐Effector Gene, Bax, Is Up‐Regulated in Vulnerable Hippocampal CA1 Neurons Following Global Ischemia

…, K Jin, RA Stetler, RP Simon… - Journal of …, 1996 - Wiley Online Library
… expression of Bax protein … Bax mRNA and protein are both expressed in CA1 before delayed
death, whereas bcl‐2 protein is not expressed. Bcl‐2 protein expression, but not that of Bax, …

Posterior left atrial adipose tissue attenuation assessed by computed tomography and recurrence of atrial fibrillation after catheter ablation

M El Mahdiui, J Simon, JM Smit… - Circulation …, 2021 - Am Heart Assoc
Background: Atrial fibrillation (AF) recurrence following catheter ablation remains high.
Recent studies have shown a relation between epicardial adipose tissue and AF. epicardial …

[HTML][HTML] Calpain-1 regulates Bax and subsequent Smac-dependent caspase-3 activation in neutrophil apoptosis

…, S Conus, A Cavalli, G Folkers, HU Simon - Journal of Biological …, 2004 - ASBMB
In the absence and in the resolution of inflammatory responses, neutrophils rapidly undergo
spontaneous apoptosis. Here we report about a new apoptosis pathway in these cells that …

'Ice rind'or 'ice pack'? A new CT feature of pulmonary haemorrhage

AJ Villanueva, AMV Campos, S Bax… - Clinical …, 2022 - clinicalradiologyonline.net
A pictorial review of five cases of anomalous coronary anatomy in young patients. The
cases draw from cardiac computed tomography (CT) imaging. In this review, examples are …